Epidemiology of acute kidney injury in intensive care units in Beijing: the multi-center BAKIT study

Background Acute kidney injury (AKI) commonly occurs in intensive care units (ICUs), leading to adverse clinical outcomes and increasing costs. However, there are limited epidemiological data of AKI in the critically ill in Beijing, China. Methods In this prospective cohort study in 30 ICUs, we scre...

Full description

Saved in:
Bibliographic Details
Published in:BMC Nephrology 2019, Vol.20 (1)
Main Authors: Jiang, Li, Zhu, Yibing, Luo, Xuying, Wen, Ying, Du, Bin, Wang, Meiping, Zhao, Zhen, Yin, Yanyan, Zhu, Bo, Xi, Xiuming, Xu, Yuan, Zhou, Jianxin, Li, Ang, Liu, Jingyuan, Li, Wenxiong, Chen, Wenjin, Jia, Jianguo, Zhu, Xi, Ma, Penglin, Chen, Wei, Wang, Dongxin, An, Youzhong, Zhan, Qingyuan, Li, Gang, Zhang, Haitao, Ning, Bo, He, Zhongjie, Zhang, Zhicheng, Sun, Yaxiong, Jia, Shijie, Liu, Yalin, Cheng, Rui, Song, Qing, Liu, Jinning, Chao, Yangong, Li, Huizhen, Feng, Li, Shi, Ruochun, Jiang, Qi, Wang, Peng, Deng, Yujie, Sun, Yan, Zhang, Xin, Zhang, Li, Wang, Ying, Lou, Ran, Wang, Jing
Format: Report
Language:English
Subjects:
Anticoagulants
Care and treatment
China
Comparative analysis
Critical care medicine
Epidemiology
Mortality
Septic shock
Shock
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Acute kidney injury (AKI) commonly occurs in intensive care units (ICUs), leading to adverse clinical outcomes and increasing costs. However, there are limited epidemiological data of AKI in the critically ill in Beijing, China. Methods In this prospective cohort study in 30 ICUs, we screened the patients up to 10 days after ICU admission. Characteristics and outcomes were compared between AKI and non-AKI, renal replacement therapy (RRT) and non-RRT patients. Nomograms of logistic regression and Cox regression were performed to examine potential risk factors for AKI and mortality. Results A total of 3107 patients were included in the final analysis. The incidence of AKI was 51.0%; stages 1 to 3 accounted for 23.1, 11.8, and 15.7%, respectively. The majority (87.6%) of patients with AKI developed AKI on the first 4 days after admission to the ICU. A total of 281 patients were treated with RRT. Continuous RRT with predilution, citrate for anticoagulation and femoral vein for vascular access was the most common RRT pattern (29.9%, 84 of 281). Patients with AKI were associated with longer ICU-LOS and higher mortality and costs (P
ISSN:1471-2369
1471-2369
DOI:10.1186/s12882-019-1660-z