Psychosomatische Medizin in der Gutenberg-Gesundheitsstudie --research questions, measurement instruments, selected results

Goal: Main questions from the Gutenberg Health Study (GHS) related to psychosomatic medicine are presented: (1) Prevalence and incidence of mental illnesses, (2) Sex-specific risk- and protective factors for mental health, (3) Interplay between psychological and somatic diseases and (4) methodical-p...

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Published in:Zeitschrift fur Psychosomatische Medizin und Psychotherapie 2020, Vol.66 (4), p.355
Main Authors: Beutel, Manfred E, Tibubos, Ana Nanette, Michal, Matthias, Wiltink, Jörg, Otten, Daniëlle, Werner, Antonia, Münzel, Thomas, Lackner, Karl J, Pfeiffer, Norbert, König, Jochem, Brähler, Elmar
Format: Report
Language:ger
Subjects:
Atherosclerosis
Comorbidity
Depression, Mental
Measurement
Measuring instruments
Mental health
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Summary:Goal: Main questions from the Gutenberg Health Study (GHS) related to psychosomatic medicine are presented: (1) Prevalence and incidence of mental illnesses, (2) Sex-specific risk- and protective factors for mental health, (3) Interplay between psychological and somatic diseases and (4) methodical-psychometric developments. Methods: The GHS is an ongoing, prospective and interdisciplinary cohort study in Mainz. The comprehensive examinations include psychological characteristics and clinical and laboratory tests. 15010 respondents were selected in the baseline study from 2007 until 2012 and re-examined after 2.5 years and 5 years. Results: Of the first 5000 respondents in the baseline study 413 women (8.7 %) and 276 men (5.8 %) indicated depressive symptoms (PHQ-9 > = 10). After five years, half of the participants with depressive symptoms at baseline also indicated depressive symptoms five years later. Risk factors for men were a lack of social support, for women smoking and Type D personality. The proportion of new cases of depression at follow-up was 4.4 %. Risk factors were symptoms of anxiety, Type D, smoking and comorbid cancer. Protective were age and social support. Findings on the association of physical and mental disorders and their behavioral and biological links (atherosclerosis, inflammation) are presented. Discussion: Prospective assessment of biological, psychological and social parameters offers the possibility to study their interplay in the development of mental and somatic illnesses. Key words Mental Health - Psychosomatic Medicine - Gutenberg Health Study Fragestellung: Vorgestellt werden die Hauptfragestellungen in der Gutenberg-Gesundheitsstudie (GHS) von Seiten der Psychosomatischen Medizin: (1) Prävalenz und Inzidenz psychischer Erkrankungen, (2) Geschlechtsbezogene Risiko- und Schutzfaktoren für psychische Gesundheit, (3) Wechselwirkungen psychischer und somatischer Erkrankungen und (4) methodisch-psychometrische Entwicklungen. Methode: Die GHS ist eine laufende, prospektive und interdisziplinäre Kohortenstudie in Mainz. Die umfassenden Untersuchungen im Studienzentrum schließen neben psychischen Merkmalen klinische- und Laboruntersuchungen ein. In der Basiserhebung von 2007 bis 2012 wurden 15010 Teilnehmerinnen und Teilnehmer rekrutiert. Diese wurden nach zweieinhalb Jahren telefonisch und nach fünf Jahren eingehend nachuntersucht. Ergebnisse: Von den ersten 5000 Teilnehmenden in der Basiserhebung zeigten 413 Frauen (8.7 %) und 2
ISSN:1438-3608