Five-year changes in objectively measured cardiorespiratory fitness, physical activity, and sedentary time in mid-to-late adulthood

• Published in: Applied physiology, nutrition, and metabolism nutrition, and metabolism, 2022-02, Vol.47 (2), p.206-209
• Main Authors: Dougherty, Ryan J, Lose, Sarah R, Gaitán, Julian M, Mergen, Brandon M, Chin, Nathaniel A, Okonkwo, Ozioma C, Cook, Dane B
• Format: Article
• Language: English
• Subjects: accelerometer; Accelerometry; accéléromètre; Adulthood; Adults; aerobic fitness; Aged; Alzheimer's disease; apolipoprotein E4; Apolipoprotein E4 - blood; Apolipoproteins; apolipoprotéine E4; aptitude aérobie; Cardiopulmonary system; Cardiorespiratory Fitness; Cardiovascular system; condition physique; Demographic aspects; exercice physique; Exercise; Exercise - trends; Exercise Test; facteur de risque; facteurs liés au mode de vie; Female; Forecasts and trends; Genetic aspects; Genetics; Health aspects; Health behavior; Health risks; Humans; lifestyle factors; longitudinal assessment; Male; Middle age; Middle Aged; Older people; Physical fitness; Respiration; Respiratory organs; risk factor; Risk factors; Sedentary Behavior; évaluation longitudinale
• ISSN: 1715-5312; 1715-5320
• DOI: 10.1139/apnm-2021-0500

This study examined 5-year changes in cardiorespiratory fitness, physical activity, and sedentary time in mid-to-late aged adults. Fifty-seven participants completed baseline and follow-up treadmill exercise tests and physical activity monitoring. We observed a 14% decline in fitness (p < 0.001), 12% decrease in physical activity (p = 0.010), and non-significant increase in sedentary time (p = 0.196). Age was negatively associated with 5-year change in physical activity (r = −0.31; p = 0.02) and this decline was strongest among APOE ε4 carriers (g = −0.75). Novelty: Cardiorespiratory fitness and physical activity significantly declined from mid-to-late adulthood, these findings were most pronounced among older adults and those with genetic risk for Alzheimer’s disease.