An "off-on" electrochemiluminescence aptasensor for microcystin-LR assay based on the resonance energy transfer from PTCA/NH.sub.2-MIL-125 to gold nanoparticles

A novel "off-on" electrochemiluminescence (ECL) aptasensor based on ECL resonance energy transfer (RET) system from 3,4,9,10-perylenetetracar-boxylic acid/the metal-organic frameworks NH.sub.2-MIL-125(Ti) (PTCA/NH.sub.2-MIL-125) to Au nanoparticles (Au NPs) was put forward for microcystin-...

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Bibliographic Details
Published in:Mikrochimica acta (1966) 2020-08, Vol.187 (8)
Main Authors: Li, Jingxian, Jiang, Ding, Shan, Xueling, Wang, Wenchang, Chen, Zhidong
Format: Article
Language:English
Subjects:
Nanoparticles
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Summary:A novel "off-on" electrochemiluminescence (ECL) aptasensor based on ECL resonance energy transfer (RET) system from 3,4,9,10-perylenetetracar-boxylic acid/the metal-organic frameworks NH.sub.2-MIL-125(Ti) (PTCA/NH.sub.2-MIL-125) to Au nanoparticles (Au NPs) was put forward for microcystin-LR (MC-LR) assay. The electrochemiluminescence (ECL) emission spectra of PTCA/NH.sub.2-MIL-125 show excellent spectral overlap with the UV-vis absorption spectrum of Au NPs. A linear response ranging from 10 fM (9.95 x 10.sup.-6 [mu]g L.sup.-1) to 0.1 [mu]M (99.5 [mu]g L.sup.-1) was obtained, and the detection limit was 3.6 fM (3.58 x 10.sup.-6 [mu]g L.sup.-1) under optimal conditions at a potential of - 1.6 V (S/N = 3). Besides, the prepared ECL-RET MC-LR aptasensor exhibited good selectivity and stability.
ISSN:0026-3672
DOI:10.1007/s00604-020-04453-x