Synthesis of First Representatives of Isatin 1,2,3-Thiadiazolylcarbonylhydrazones

The synthesis of new isatin derivatives containing the 1,2,3-thiadiazole ring in the hydrazone fragment was carried out. It was shown that the obtained compounds do not possess a hemolytic effect and do not exhibit cytotoxicity with respect to normal Chang liver human cell lines.

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Bibliographic Details
Published in:Russian journal of general chemistry 2020-05, Vol.90 (5), p.917-920
Main Authors: Bogdanov, A. V., Gil’fanova, A. R., Voloshina, A. D., Shakhmina, Yu. S., Kalinina, T. A., Glukhareva, T. V., Mironov, V. F.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
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Description
Summary:The synthesis of new isatin derivatives containing the 1,2,3-thiadiazole ring in the hydrazone fragment was carried out. It was shown that the obtained compounds do not possess a hemolytic effect and do not exhibit cytotoxicity with respect to normal Chang liver human cell lines.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363220050278