IMA Levels in Cord Blood Plasma in Pre-eclampsia

Pre-eclampsia is associated with ischemia and increased oxidative stress in maternal circulation extending to neonates also. This effect may lead to modification of plasma albumin to ischemia modified albumin (IMA). The effect of pre-eclampsia on plasma levels of IMA was assessed in cord blood sampl...

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Bibliographic Details
Published in:Indian journal of clinical biochemistry 2014-12, Vol.29 (S1), p.S49
Main Authors: Dahiya, Kiran, Kulshreshtha, Manish Raj, Bansal, Piyush, Singh, Veena, Sachdeva, Ashuma
Format: Article
Language:English
Subjects:
Comparative analysis
Ischemia
Preeclampsia
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Summary:Pre-eclampsia is associated with ischemia and increased oxidative stress in maternal circulation extending to neonates also. This effect may lead to modification of plasma albumin to ischemia modified albumin (IMA). The effect of pre-eclampsia on plasma levels of IMA was assessed in cord blood samples and compared with healthy neonates. IMA levels were estimated in cord blood of thirty newborns born to pre-eclamptic mothers and compared with thirty normal newborns. IMA was estimated colorimetrically and the results were compared statistically. The levels of IMA were found to be significantly higher (P
ISSN:0970-1915