Marine Organisms as a Prolific Source of Bioactive Depsipeptides

Depsipeptides, an important group of polypeptides containing residues of hydroxy acids and amino acids linked together by amide and ester bonds, have potential applications in agriculture and medicine. A growing body of evidence demonstrates that marine organisms are prolific sources of depsipeptide...

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Bibliographic Details
Published in:Marine Drugs 2023, Vol.21 (2)
Main Authors: Zeng, Mingyuan, Tao, Jianyun, Xu, Shuang, Bai, Xuelian, Zhang, Huawei
Format: Report
Language:English
Subjects:
Biopolymers
Composition
Health aspects
Marine biology
Methods
Natural products
Online Access:Get full text
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Summary:Depsipeptides, an important group of polypeptides containing residues of hydroxy acids and amino acids linked together by amide and ester bonds, have potential applications in agriculture and medicine. A growing body of evidence demonstrates that marine organisms are prolific sources of depsipeptides, such as marine cyanobacteria, sponges, mollusks, microorganisms and algae. However, these substances have not yet been comprehensively summarized. In order to enrich our knowledge about marine depsipeptides, their biological sources and structural features, as well as bioactivities, are highlighted in this review after an extensive literature search and data analysis.
ISSN:1660-3397
1660-3397
DOI:10.3390/md21020120