Natural TCRs targeting [KRAS.sup.G12V] display fine specificity and sensitivity to human solid tumors

TRIAL REGISTRATION. ClinicalTrials.gov NCT03592888.

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Bibliographic Details
Published in:Journal of Clinical Investigation 2024, Vol.134 (21)
Main Authors: Bear, Adham S, Nadler, Rebecca B, O'Hara, Mark H, Stanton, Kelsey L, Xu, Chong, Saporito, Robert J, Rech, Andrew J, Baroja, Miren L, Blanchard, Tatiana, Elliott, Maxwell H, Ford, Michael J, Jones, Richard, Patel, Shivang, Brennan, Andrea, O'Neil, Zachary, Powell, Daniel J., Jr, Vonderheide, Robert H, Linette, Gerald P, Carreno, Beatriz M
Format: Report
Language:English
Subjects:
Antigen receptors, T cell
Cancer
Cancer vaccines
Cellular therapy
Gene mutations
Health aspects
Oncogenes
Oncology, Experimental
Receptors
T cells
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Description
Summary:TRIAL REGISTRATION. ClinicalTrials.gov NCT03592888.
ISSN:0021-9738
DOI:10.1172/JCI175790