Loading…

Design, activity, and 2.8 angstrom crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease

Saved in:

Bibliographic Details
Published in:	Science (American Association for the Advancement of Science) 1990-08, Vol.249 (4968), p.527
Main Authors:	Erickson, John, Neidhart, David J, VanDrie, John, Kempf, Dale J, Wang, Xiu Chun, Norbeck, Daniel W, Plattner, Jacob J, Rittenhouse, Judith W, Turon, Mary, Wideburg, Norman, Kohlbrenner, William E, Simmer, Robert, Helfrich, Rosalind, Paul, Deborah A, Knigge, Mark
Format:	Article
Language:	English
Subjects:	Analysis Atomic structure Electronic structure HIV HIV (Viruses) Protease inhibitors
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

cited_by
cites
container_end_page
container_issue	4968
container_start_page	527
container_title	Science (American Association for the Advancement of Science)
container_volume	249
creator	Erickson, John Neidhart, David J VanDrie, John Kempf, Dale J Wang, Xiu Chun Norbeck, Daniel W Plattner, Jacob J Rittenhouse, Judith W Turon, Mary Wideburg, Norman Kohlbrenner, William E Simmer, Robert Helfrich, Rosalind Paul, Deborah A Knigge, Mark
description
format	article
fullrecord	<record><control><sourceid>gale</sourceid><recordid>TN_cdi_gale_infotracgeneralonefile_A9353363</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A9353363</galeid><sourcerecordid>A9353363</sourcerecordid><originalsourceid>FETCH-LOGICAL-g2373-44a35d00c2d007b14c48b16185611d2b8ca58c49abc5016d022d32cb7764dff73</originalsourceid><addsrcrecordid>eNqN0E1LwzAYAOAiCs7pf8jNw1bJRz-Ps-o2GO6g7jrS5G2NpM1IMln_vQEFFXYYgffz4T3kLBoRXKZxSTE7j0YYsywucJ5eRlfOfWAcdiUbRfoBnGr7KeLCq0_lh1D1EtG7IuTWeWs6JOzgPNcodHvh9xaQaRBHFUVu6DrwVgmk-ndVK28sEqbbaTiARN6gxXITE7SzxgN3cB1dNFw7uPnJ4-jt6fG1WsSr9XxZzVZxS1nO4iThLJUYCxpCXpNEJEVNMlKkGSGS1oXgaSGSktcixSSTmFLJqKjzPEtk0-RsHE2-77Zcw1b1jfGWixZ6sFybHhoVxrOSpYxlLOjpER2ehE6JI_z2Hw_Cw8G3fO_cdvnyfKpcb06V9_MTZTFf_ZWTY1IYraGFbfjwav2rvwA5E6qo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Design, activity, and 2.8 angstrom crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease</title><source>American Association for the Advancement of Science</source><source>Social Science Premium Collection</source><source>Education Collection</source><creator>Erickson, John ; Neidhart, David J ; VanDrie, John ; Kempf, Dale J ; Wang, Xiu Chun ; Norbeck, Daniel W ; Plattner, Jacob J ; Rittenhouse, Judith W ; Turon, Mary ; Wideburg, Norman ; Kohlbrenner, William E ; Simmer, Robert ; Helfrich, Rosalind ; Paul, Deborah A ; Knigge, Mark</creator><creatorcontrib>Erickson, John ; Neidhart, David J ; VanDrie, John ; Kempf, Dale J ; Wang, Xiu Chun ; Norbeck, Daniel W ; Plattner, Jacob J ; Rittenhouse, Judith W ; Turon, Mary ; Wideburg, Norman ; Kohlbrenner, William E ; Simmer, Robert ; Helfrich, Rosalind ; Paul, Deborah A ; Knigge, Mark</creatorcontrib><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><language>eng</language><publisher>American Association for the Advancement of Science</publisher><subject>Analysis ; Atomic structure ; Electronic structure ; HIV ; HIV (Viruses) ; Protease inhibitors</subject><ispartof>Science (American Association for the Advancement of Science), 1990-08, Vol.249 (4968), p.527</ispartof><rights>COPYRIGHT 1990 American Association for the Advancement of Science</rights><rights>COPYRIGHT 1990 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Erickson, John</creatorcontrib><creatorcontrib>Neidhart, David J</creatorcontrib><creatorcontrib>VanDrie, John</creatorcontrib><creatorcontrib>Kempf, Dale J</creatorcontrib><creatorcontrib>Wang, Xiu Chun</creatorcontrib><creatorcontrib>Norbeck, Daniel W</creatorcontrib><creatorcontrib>Plattner, Jacob J</creatorcontrib><creatorcontrib>Rittenhouse, Judith W</creatorcontrib><creatorcontrib>Turon, Mary</creatorcontrib><creatorcontrib>Wideburg, Norman</creatorcontrib><creatorcontrib>Kohlbrenner, William E</creatorcontrib><creatorcontrib>Simmer, Robert</creatorcontrib><creatorcontrib>Helfrich, Rosalind</creatorcontrib><creatorcontrib>Paul, Deborah A</creatorcontrib><creatorcontrib>Knigge, Mark</creatorcontrib><title>Design, activity, and 2.8 angstrom crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><subject>Analysis</subject><subject>Atomic structure</subject><subject>Electronic structure</subject><subject>HIV</subject><subject>HIV (Viruses)</subject><subject>Protease inhibitors</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><recordid>eNqN0E1LwzAYAOAiCs7pf8jNw1bJRz-Ps-o2GO6g7jrS5G2NpM1IMln_vQEFFXYYgffz4T3kLBoRXKZxSTE7j0YYsywucJ5eRlfOfWAcdiUbRfoBnGr7KeLCq0_lh1D1EtG7IuTWeWs6JOzgPNcodHvh9xaQaRBHFUVu6DrwVgmk-ndVK28sEqbbaTiARN6gxXITE7SzxgN3cB1dNFw7uPnJ4-jt6fG1WsSr9XxZzVZxS1nO4iThLJUYCxpCXpNEJEVNMlKkGSGS1oXgaSGSktcixSSTmFLJqKjzPEtk0-RsHE2-77Zcw1b1jfGWixZ6sFybHhoVxrOSpYxlLOjpER2ehE6JI_z2Hw_Cw8G3fO_cdvnyfKpcb06V9_MTZTFf_ZWTY1IYraGFbfjwav2rvwA5E6qo</recordid><startdate>19900803</startdate><enddate>19900803</enddate><creator>Erickson, John</creator><creator>Neidhart, David J</creator><creator>VanDrie, John</creator><creator>Kempf, Dale J</creator><creator>Wang, Xiu Chun</creator><creator>Norbeck, Daniel W</creator><creator>Plattner, Jacob J</creator><creator>Rittenhouse, Judith W</creator><creator>Turon, Mary</creator><creator>Wideburg, Norman</creator><creator>Kohlbrenner, William E</creator><creator>Simmer, Robert</creator><creator>Helfrich, Rosalind</creator><creator>Paul, Deborah A</creator><creator>Knigge, Mark</creator><general>American Association for the Advancement of Science</general><scope>8GL</scope><scope>IBG</scope><scope>IOV</scope><scope>ISN</scope></search><sort><creationdate>19900803</creationdate><title>Design, activity, and 2.8 angstrom crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease</title><author>Erickson, John ; Neidhart, David J ; VanDrie, John ; Kempf, Dale J ; Wang, Xiu Chun ; Norbeck, Daniel W ; Plattner, Jacob J ; Rittenhouse, Judith W ; Turon, Mary ; Wideburg, Norman ; Kohlbrenner, William E ; Simmer, Robert ; Helfrich, Rosalind ; Paul, Deborah A ; Knigge, Mark</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g2373-44a35d00c2d007b14c48b16185611d2b8ca58c49abc5016d022d32cb7764dff73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Analysis</topic><topic>Atomic structure</topic><topic>Electronic structure</topic><topic>HIV</topic><topic>HIV (Viruses)</topic><topic>Protease inhibitors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Erickson, John</creatorcontrib><creatorcontrib>Neidhart, David J</creatorcontrib><creatorcontrib>VanDrie, John</creatorcontrib><creatorcontrib>Kempf, Dale J</creatorcontrib><creatorcontrib>Wang, Xiu Chun</creatorcontrib><creatorcontrib>Norbeck, Daniel W</creatorcontrib><creatorcontrib>Plattner, Jacob J</creatorcontrib><creatorcontrib>Rittenhouse, Judith W</creatorcontrib><creatorcontrib>Turon, Mary</creatorcontrib><creatorcontrib>Wideburg, Norman</creatorcontrib><creatorcontrib>Kohlbrenner, William E</creatorcontrib><creatorcontrib>Simmer, Robert</creatorcontrib><creatorcontrib>Helfrich, Rosalind</creatorcontrib><creatorcontrib>Paul, Deborah A</creatorcontrib><creatorcontrib>Knigge, Mark</creatorcontrib><collection>Gale In Context: High School</collection><collection>Biography (Gale in Context)</collection><collection>Gale in Context : Opposing Viewpoints</collection><collection>Gale In Context: Canada</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Erickson, John</au><au>Neidhart, David J</au><au>VanDrie, John</au><au>Kempf, Dale J</au><au>Wang, Xiu Chun</au><au>Norbeck, Daniel W</au><au>Plattner, Jacob J</au><au>Rittenhouse, Judith W</au><au>Turon, Mary</au><au>Wideburg, Norman</au><au>Kohlbrenner, William E</au><au>Simmer, Robert</au><au>Helfrich, Rosalind</au><au>Paul, Deborah A</au><au>Knigge, Mark</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Design, activity, and 2.8 angstrom crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1990-08-03</date><risdate>1990</risdate><volume>249</volume><issue>4968</issue><spage>527</spage><pages>527-</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><pub>American Association for the Advancement of Science</pub><tpages>7</tpages></addata></record>
fulltext	fulltext
identifier	ISSN: 0036-8075
ispartof	Science (American Association for the Advancement of Science), 1990-08, Vol.249 (4968), p.527
issn	0036-8075 1095-9203
language	eng
recordid	cdi_gale_infotracgeneralonefile_A9353363
source	American Association for the Advancement of Science; Social Science Premium Collection; Education Collection
subjects	Analysis Atomic structure Electronic structure HIV HIV (Viruses) Protease inhibitors
title	Design, activity, and 2.8 angstrom crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease
url	http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T12%3A48%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Design,%20activity,%20and%202.8%20angstrom%20crystal%20structure%20of%20a%20C2%20symmetric%20inhibitor%20complexed%20to%20HIV-1%20protease&rft.jtitle=Science%20(American%20Association%20for%20the%20Advancement%20of%20Science)&rft.au=Erickson,%20John&rft.date=1990-08-03&rft.volume=249&rft.issue=4968&rft.spage=527&rft.pages=527-&rft.issn=0036-8075&rft.eissn=1095-9203&rft_id=info:doi/&rft_dat=%3Cgale%3EA9353363%3C/gale%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-g2373-44a35d00c2d007b14c48b16185611d2b8ca58c49abc5016d022d32cb7764dff73%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rft_galeid=A9353363&rfr_iscdi=true