Efficacy of preoperative antimicrobial skin preparation solutions on biofilm bacteria

ABSTRACT • RESEARCH ON THE MEDICAL EFFICACY of topical antimicrobials and antibiotics against infections has focused largely on the effect on free-floating, planktonic bacteria. • IN THE PRESENCE OF nonbiological surfaces (eg, catheters, prosthetic devices, biomaterials), however, bacteria form high...

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Bibliographic Details
Published in:AORN journal 2005-03, Vol.81 (3), p.491,497-495,501
Main Author: Paulson, Daryl S.
Format: Article
Language:English
Subjects:
Preoperative care
Surgical scrub
Tests, problems and exercises
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Summary:ABSTRACT • RESEARCH ON THE MEDICAL EFFICACY of topical antimicrobials and antibiotics against infections has focused largely on the effect on free-floating, planktonic bacteria. • IN THE PRESENCE OF nonbiological surfaces (eg, catheters, prosthetic devices, biomaterials), however, bacteria form highly complex biofilm systems that resist traditional medical treatment. • BACTERIAL PATHOGENS commonly found in chronic infections in both the planktonic and biofilm stae were challenged with a variety of commonly used topical antimicrobial formulations. • BIOFILM BACTERIA were shown to be more resistant to killing than planktonic bacteria. Antimicrobial skin preparation times were adequate to significantly reduce bacterial populations protected in biofilms. AORN J 81 (March 2005) 492-501.
ISSN:0001-2092
1878-0369
DOI:10.1016/S0001-2092(06)60436-5