Morphoquantitative analysis of the intraepithelial neoplasic uterine cells by computer image system/Analisis morfocuantitativo de las celulas neoplasicas intraepiteliales uterinas por sistema computarizado

The purpose of the present research was to detect the DNA variations by Feulgen stained chromatin and the packing degree of the cervical chromatin in the clinical cases of human uterine carcinomas. Scanning microphotometry was carried out on slides prepared from block Feulgen-stained. Accurate contr...

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Bibliographic Details
Published in:International journal of morphology 2008-03, Vol.26 (1), p.93
Main Authors: Lima, Jacqueline Silva Brito, Bittencourt, Alexandre Motta, Lima, Carlos Eduardo de Queiroz, da Mota, Diogenes Luis, Romaguera, Ana Maria de Ataide, da Silva, Luiz Lucio Soares
Format: Article
Language:Spanish
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Summary:The purpose of the present research was to detect the DNA variations by Feulgen stained chromatin and the packing degree of the cervical chromatin in the clinical cases of human uterine carcinomas. Scanning microphotometry was carried out on slides prepared from block Feulgen-stained. Accurate control procedures were performed using normal human cell nuclei. The cervical cells was morphometric studied using the Image Lab System for citologic classification. The overall diagnostic accuracy for neoplasia type I (CIN I) and type II (CIN II), demonstrated by stain interpetration values of a sensitive detection of DNA neuroploidy and a significant difference between the two groups in scanning static cytophotometry.
ISSN:0717-9367