Hepatocellular carcinoma with polymyositis as an initial symptom: a case report

Patients with hepatocellular carcinoma may manifest paraneoplastic syndromes such as hypercholesterolaemia, hypoglycaemia, hypercalcaemia and erythrocytosis. An exceptional case of hepatocellular carcinoma associated with polymyositis, a rheumatic paraneoplastic syndrome, is reported. A 72-year-old...

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Bibliographic Details
Published in:Acta clinica belgica (English ed. Online) 2011-01, Vol.66 (1), p.53
Main Authors: Tekaya, R, Abdelghni, K, Abdelmoula, L, Ben Hadj Yahia, C, Chaabouni, L, Zouari, R
Format: Article
Language:English
Subjects:
Creatine kinase
Diagnosis
Hepatoma
Liver cancer
Polymyositis
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Summary:Patients with hepatocellular carcinoma may manifest paraneoplastic syndromes such as hypercholesterolaemia, hypoglycaemia, hypercalcaemia and erythrocytosis. An exceptional case of hepatocellular carcinoma associated with polymyositis, a rheumatic paraneoplastic syndrome, is reported. A 72-year-old male complained for a recent muscular weakness mainly in the proximal limb muscles. The clinical course, a raised level of serum creatine kinase and electromyographic findings suggested polymyositis, and the pathological findings on muscle biopsy were compatible with this diagnosis. Computed tomography of the upper abdomen revealed a mass lesion in segment IV, V and VII of the liver, and alpha foetoprotein level was high, resulting in the diagnosis of hepatocellular carcinoma. Key words: polymyositis, hepatocellular carcinoma, paraneoplastic
ISSN:1784-3286
DOI:10.2143/ACB.66.1.2062515