Greasy tags for protein removal: most proteins in the human body are difficult targets for small-molecule drugs. This problem may have been overcome with the discovery of molecules that induce protein degradation, suggesting fresh, modular approaches to drug discovery

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Bibliographic Details
Published in:Nature (London) 2012-07, Vol.487 (7407), p.308
Main Authors: Neklesa, Taavi K, Crews, Craig M
Format: Article
Language:English
Subjects:
Binding proteins
DNA barcoding
Pharmaceutical research
Properties
Proteolysis
Online Access:Get full text
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ISSN:0028-0836
1476-4687