Relationship between depression in patients with COPD and the percent of predicted [FEV.sub.1], BODE index, and health-related quality of life

BACKGROUND: We investigated the prevalence of depression among patients with COPD treated in long-term in-patient rehabilitation facilities, using the Center for Epidemiologic Studies Depression scale (CES-D). Furthermore, the relationship between the severity of air-flow obstruction (the percent of...

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Bibliographic Details
Published in:Respiratory care 2013-02, Vol.58 (2), p.334
Main Authors: Iguchi, Asuka, Senjyu, Hideaki, Hayashi, Yoshika, Kanada, Rumi, Iwai, Shoko, Honda, Sumihisa, Kitagawa, Chika, Ozawa, Hiroki, Rikitomi, Naoto
Format: Article
Language:English
Subjects:
Demographic aspects
Depression, Mental
Lung diseases, Obstructive
Prognosis
Quality of life
Risk factors
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Summary:BACKGROUND: We investigated the prevalence of depression among patients with COPD treated in long-term in-patient rehabilitation facilities, using the Center for Epidemiologic Studies Depression scale (CES-D). Furthermore, the relationship between the severity of air-flow obstruction (the percent of predicted [FEV.sub.1]), BODE (body mass index, degree of air-flow obstruction, dyspnea, exercise capacity) index, health-related quality of life (St George's Respiratory Questionnaire [SGRQ]), and depression were investigated. METHODS: We recruited 74 in-patients (64 males, 10 females) with COPD. The mean age of the subjects was 72.7 years (range 52-85 y). Subjects completed the CES-D, and measurements were made of pulmonary function, body mass index, Modified Medical Research Council dyspnea scale, 6-min walk test (6MWT), and SGRQ. RESULTS: Depression was evident in 48.6% (n = 36) of the subjects. A weak correlation was found between the CES-D scores and the percent of predicted [FEV.sub.1]. The prevalence of depression showed a significant association with BODE stage. Scores for the SGRQ activity and impacts domains, and total SGRQ score were significantly worse in the subjects who were depressed. CONCLUSIONS: We found a high prevalence of depression among patients with stable COPD treated in long-term in-patient rehabilitation facilities. Depression among these patients, as measured by the CES-D, was associated with greater impairment in respiratory function and with poorer Modified Medical Research Council dyspnea scale and SGRQ scores. The prevalence of depression increased with BODE stage. Key words: COPD; depression; [FEV.sub.1]: BODE index; CES-D; quality of life. [Respir Care 2013;58(2):334-339. [C] 2013 Daedalus Enterprises]'
ISSN:0020-1324
DOI:10.4187/respcare.01844