Polyfunctional pyrazoles. 7. Ethyl 1-aryl-4-formylpyrazole-3-carboxylates in the synthesis of 2-aryl-2,4-dihydro-6H-thieno-[3,4-c]pyrazol-6-ones

A convenient method has been developed for the synthesis of 2,4-dihydro-6 H -thieno[3,4- c ]pyrazol-6-ones by means of an intramolecular cyclization of 4-sulfanylmethylpyrazole-3-carboxylic acids. The latter were prepared from ethyl 4-formylpyrazole-3-carboxylates via the intermediate 4-hydroxy-meth...

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Bibliographic Details
Published in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2013, Vol.48 (10), p.1545-1549
Main Authors: Bratenko, M. K., Barus, M. M., Vovk, M. V.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Organic acids
Organic Chemistry
Pharmacy
Resveratrol
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Summary:A convenient method has been developed for the synthesis of 2,4-dihydro-6 H -thieno[3,4- c ]pyrazol-6-ones by means of an intramolecular cyclization of 4-sulfanylmethylpyrazole-3-carboxylic acids. The latter were prepared from ethyl 4-formylpyrazole-3-carboxylates via the intermediate 4-hydroxy-methyl-, 4-chloromethyl-, and 4-thioureidomethyl derivatives.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-013-1171-y