A new lupane triterpenoid from the aerial part of Acanthopanax trifoliatus

A new lupane-triterpene carboxylic acid ( 1 ), together with two known 24-nor-lupane-triterpene carboxylic acids, 24-nor-11 α -hydroxy-3-oxo-lup-20(29)-en-28-oic acid and 24-nor-3 α ,11 α -dihydroxy-lup-20(29)-en-28-oic acid, were isolated from the aerial part of Acanthopanax trifoliatus. The struct...

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Bibliographic Details
Published in:Chemistry of natural compounds 2013-05, Vol.49 (2), p.274-276
Main Authors: Tam, Nguyen Thanh, Thien, Dao Duc, Nhung, Le Thi Hong, Van Chien, Tran, Van Sung, Tran
Format: Article
Language:English
Subjects:
Medicine
Medicine, Botanic
Medicine, Herbal
Organic acids
Organic Chemistry
Pharmacy
Plant Sciences
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Summary:A new lupane-triterpene carboxylic acid ( 1 ), together with two known 24-nor-lupane-triterpene carboxylic acids, 24-nor-11 α -hydroxy-3-oxo-lup-20(29)-en-28-oic acid and 24-nor-3 α ,11 α -dihydroxy-lup-20(29)-en-28-oic acid, were isolated from the aerial part of Acanthopanax trifoliatus. The structure of 1 was determined to be 11 α ,23-dihydroxy-3-oxo-lup-20(29)-en-28-oic acid on the basis of spectroscopic data, including IR, HR-ESI-MS, PMR, 13 C NMR, 1 H- 1 H COSY, HSQC, and HMBC, and comparison with published references.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-013-0580-6