The effects of secondhand smoke on postoperative pain and fentanyl consumption

Background Although the need for increased postoperative analgesia in smokers has been described, the effect of secondhand smoke on postoperative analgesia requirements has not been studied. We examined the effects of secondhand smoke on fentanyl consumption and postoperative pain. Methods In this s...

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Bibliographic Details
Published in:Journal of anesthesia 2013-08, Vol.27 (4), p.569-574
Main Authors: Aydogan, Mustafa Said, Ozturk, Erdogan, Erdogan, Mehmet Ali, Yucel, Aytac, Durmus, Mahmut, Ersoy, Mehmet Ozcan, Colak, Cemil
Format: Article
Language:English
Subjects:
Adult
Aged
Analysis
Anesthesiology
Anesthetics, Intravenous - administration & dosage
Consumption data
Critical Care Medicine
Emergency Medicine
Female
Fentanyl
Fentanyl - administration & dosage
Humans
Intensive
Medicine
Medicine & Public Health
Middle Aged
Original Article
Pain Measurement - methods
Pain Medicine
Pain, Postoperative
Pain, Postoperative - chemically induced
Pain, Postoperative - drug therapy
Passive smoking
Piperidines - administration & dosage
Propofol - administration & dosage
Prospective Studies
Retrospective Studies
Tobacco Smoke Pollution - adverse effects
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Summary:Background Although the need for increased postoperative analgesia in smokers has been described, the effect of secondhand smoke on postoperative analgesia requirements has not been studied. We examined the effects of secondhand smoke on fentanyl consumption and postoperative pain. Methods In this study, 101 patients (American Society of Anesthesiology physical status I and II) who underwent abdominal hysterectomy were divided into 3 groups according to history of exposure to cigarette smoke as per medical records which was retrospectively confirmed by measurement of serum cotinine: smokers ( n  = 28), nonsmokers ( n  = 31), and secondhand smokers ( n  = 32). All patients received propofol–remifentanil total intravenous anesthesia and used fentanyl patient controlled analgesia for postoperative pain. The fentanyl consumption visual analogue scale-pain intensity (VAS-PI) score and side effects were recorded in the postanesthesia care unit (PACU) and at 2, 4, 6, and 24 h after surgery. Results Fentanyl consumption at all the evaluation time points was significantly higher in secondhand smokers than in nonsmokers ( P  
ISSN:0913-8668
1438-8359
DOI:10.1007/s00540-013-1565-0