Mathematical modeling to optimize the product in enzyme kinetics

Optimization of product in enzyme kinetics is successful by the showers of mathematical analysis with control measures. Enzymes are an important functional aspects of all biochemical processes, as they catalyze numerous reaction taking place within living organisms. With this view, optimization and...

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Published in:Control and cybernetics 2013-04, Vol.42 (2), p.431
Main Authors: Nandi, Sumit, Ghosh, Mithun Kumar, Bhattacharya, Rupa, Roy, Priti Kumar
Format: Article
Language:English
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Enzyme kinetics
Mathematical models
Mathematical optimization
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Ghosh, Mithun Kumar
Bhattacharya, Rupa
Roy, Priti Kumar
description Optimization of product in enzyme kinetics is successful by the showers of mathematical analysis with control measures. Enzymes are an important functional aspects of all biochemical processes, as they catalyze numerous reaction taking place within living organisms. With this view, optimization and quantification of product is stressed upon and in such a context, optimal control approaches have been applied in our study. In this article, we have formulated a mathematical model of enzymatic system dynamics with control measures with a view to optimize the product as well as process conditions. Here, Pontryagin Minimum Principle is used for determination of optimal control with the help of Hamiltonian. We discuss the relevant numerical solutions for the concentration of substrate, enzyme, complex and product with respect to a specified time interval by varying control factors.
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subjects Enzyme kinetics
Mathematical models
Mathematical optimization
title Mathematical modeling to optimize the product in enzyme kinetics
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