Determination of phenylalkylamine compounds using surface-assisted desorption/ionization from amorphous silicon

A new method has been developed for the mass spectrometric determination of phenylalkylamines based on surface-assisted laser desorption/ionization (SALDI). Films of amorphous α-Si, obtained by radiofrequency sputtering have been tested as ion emitters. The high efficiency of the ionization method c...

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Bibliographic Details
Published in:Journal of analytical chemistry (New York, N.Y.) N.Y.), 2010-12, Vol.65 (14), p.1504-1510
Main Authors: Grechnikov, A. A., Borodkov, A. S., Alimpiev, S. S., Nikiforov, S. M., Simanovskii, Ya. O., Karavanskii, V. A.
Format: Article
Language:English
Subjects:
Analysis
Analytical Chemistry
Chemistry
Chemistry and Materials Science
Chromatography
Mass spectrometry
Silicon
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Summary:A new method has been developed for the mass spectrometric determination of phenylalkylamines based on surface-assisted laser desorption/ionization (SALDI). Films of amorphous α-Si, obtained by radiofrequency sputtering have been tested as ion emitters. The high efficiency of the ionization method combined with gas chromatography and the time-of-flight mass spectrometry has been demonstrated. The main analytical parameters have been determined for 12 phenylalkylamines. The detection limit for the studied compounds has been found to vary in the range 5–150 pg/mL.
ISSN:1061-9348
1608-3199
DOI:10.1134/S1061934810140108