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Study on electrochemical profiles of Valeriana medicinal plants by capillary electrophoresis

The objective of this work was to develop a high-performance capillary electrophoresis with amperometric detection ( CE-AD ) method for the determination of pharmacologically active ingredients in extracts of Valeriana medicinal plants. The method was validated for linearity, repeatability, limits o...

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Published in:Journal of analytical chemistry (New York, N.Y.) N.Y.), 2014-02, Vol.69 (2), p.179-186
Main Authors: Li, W. L., Li, M. J., Pan, Y. L., Huang, B. K., Chu, Q. C., Ye, J. N.
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Language:English
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description The objective of this work was to develop a high-performance capillary electrophoresis with amperometric detection ( CE-AD ) method for the determination of pharmacologically active ingredients in extracts of Valeriana medicinal plants. The method was validated for linearity, repeatability, limits of detection ( LODs ) and limits of quantification ( LOQs ), etc. The LODs and LOQs of eight compounds were found to be in the range from 1.0 × 10 −8 to 1.2 × 10 −7 and 3.3 × 10 −8 to 4.0 × 10 −7 g/mL, respectively. The proposed method was successfully applied for the analyses and comparison of bioactive components in Valeriana samples after a relatively simple extraction procedure, and the resultant “electrochemical profiles” can intuitively demonstrate the content diversity of each electrochemically active ingredient in Valeriana samples from different places and plant parts. It was found the content of bioactive ingredients may vary by an order of magnitude depending on natural conditions, e.g. soil, climate, humidity etc.
doi_str_mv 10.1134/S1061934814020099
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subjects Analysis
Analytical Chemistry
Chemical properties
Chemistry
Chemistry and Materials Science
Electric properties
Medicinal plants
Medicine, Botanic
Medicine, Herbal
Physiological aspects
title Study on electrochemical profiles of Valeriana medicinal plants by capillary electrophoresis
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