Cerebellar mutism syndrome after posterior fossa surgery: a report of two cases of pilocytic astrocytoma/Posterior fossa cerrahisi sonrasi ortaya cikan serebellar mutizm sendromu: pilositik astrositoma tanili iki olgunun sunumu

• Published in: Noro-Psikiyatri Arsivi 2013-12, Vol.50 (4), p.368
• Main Authors: Gunduz, Hasan Burak, Yassa, Mustafa Ilker Kuntay, Ofluoglu, Ali Ender, Postalci, Lutfu, Emel, Erhan
• Format: Article
• Language: English
• Subjects: Astrocytoma; Care and treatment; Case studies; Causes of; Mutism; Nervous system; Surgery
• ISSN: 1300-0667
• DOI: 10.4274/npa.y6311

Cerebellar mutism is a type of syndrome including decreased speech, hypotonia, ataxia and emotional instability which occurs after posterior fossa surgery. It has been first reported by Rekate et al. and Yonemasu in 1985. It is well known that long tract signs and lower cranial nerve involvement are not seen with this syndrome and understanding is preserved. However, the pathophysiology of cerebellar mutism has not been well clarified yet. It is mainly seen in patients with medulloblastoma and brainstem involvement. In this report, we present two extraordinary cases of cerebellar mutism after posterior fossa surgery. They were considered extraordinary because their hystopathological analysis results yielded pilocytic astrocytoma which is out of the predefined risk factors. (Archives of Neuropsychiatry 2013; 50:368-371) Key words: Cterebellar mutism, pilocytic astrocytoma, posterior fossa surgery Conflict of interest: The authors reported no conflict of interest related to this article. Serebellar mutizm sendromu posterior fossa cerrahisi sonrasi azalmis konusma, hipotoni, ataksi ve duygusal kararsizlik ile kendini gosteren bir sendromdur. Ilk kez 1985 yilinda ayri makalelerde Rekate ile arkadaslari ve Yonemasu tarafindan rapor edilmislerdir. Anlamanin korunmus olmasinin, uzun trakt bulgularinin ve alt kranyal sinir tutulumunun bu sendromda gorulmediginin iyi bilinmesine ragmen, serebellar mutizmin patofizyolojisi henuz ayrintili olarak aciga cikarilamamistir. Siklikla medulloblastomali ve beyin sapi tutulumu olan hastalarda gorulmektedir. Posterior fossa cerrahisi uyguladigimiz iki olgumuzda serebellar mutizm sendromu gelismistir. Kabul edilen risk faktorlerinin disinda, histopatolojik inceleme sonucunun pilositik astrositoma gelmesi nedeniyle sira disi olarak kabul ettigimiz bu iki olguyu sunmaktayiz. (Noropsikiyatri Arsivi 2013; 50:368-371) Anahtar kelimeler: Serebellar mutizm, pilositik astrositoma, posterior fossa cerrahisi Cikar catismasi: Yazarlar bu makale ile ilgili olarak herhangi bir cikar catismasi bildirmemislerdir.