Prospects of Using Brain-Derived Neurotrophic Factor for the Treatment of Optic-Nerve Neuropathy (A Review)

The literature on the use of brain-derived neurotrophic factor (BDNF) as a promising agent capable of preventing the loss of retinal ganglion cells was reviewed. Mechanisms of BDNF action and the possible pathways for delivering this protein to the retina were considered.

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2015-02, Vol.48 (11), p.699-702
Main Authors: Khalin, I. V., Musina, N. Z., Alyautdin, R. N., Romanov, B. K., Bunatyan, N. D.
Format: Article
Language:English
Subjects:
Gene therapy
Health aspects
Medicine
Molecular-Biological Problems of Drug Design and Mechanism of Drug Action
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Description
Summary:The literature on the use of brain-derived neurotrophic factor (BDNF) as a promising agent capable of preventing the loss of retinal ganglion cells was reviewed. Mechanisms of BDNF action and the possible pathways for delivering this protein to the retina were considered.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-015-1175-2