Allogeneic bone graft devitalized in liquid nitrogen--sheep experimental study/Aloenxerto osseo cortical desvitalizado com nitrogenio liquido--estudo experimental em ovelhas

This study evaluated the allogeneic cortical bone graft incorporation after submission of the harvested fragment to a bout freezing in liquid nitrogen. Six adult sheep, clinically healthy, were submitted to a 7cm ostectomy of the tibial diaphysis. The fragment was submersed in a liquid nitrogen and...

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Bibliographic Details
Published in:Ciência rural 2015-04, p.718
Main Authors: de Albuquerque, Paulo Barros, Barni, Brunna de Souza, Silva, Renato Barbosa, Pinto, Thadeu Mourao, Gianotti, Giordano Cabral, Moura, Lanucha Fidelis da Luz, Boss, Mariana Zacouteguy, Alievi, Marcelo Meller
Format: Article
Language:Spanish
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Summary:This study evaluated the allogeneic cortical bone graft incorporation after submission of the harvested fragment to a bout freezing in liquid nitrogen. Six adult sheep, clinically healthy, were submitted to a 7cm ostectomy of the tibial diaphysis. The fragment was submersed in a liquid nitrogen and implanted in another sheep missing a same-sized segment at the corresponding bone. Stabilization of the allograft in the host bone was accomplished by a dynamic compressive plate (DCP). Clinical and radiographic evaluations were performed in the immediate post-operatory period and in every 30 days for six months after surgery. The proximal and distal host-graft interfaces showed radiographic union at a mean postoperative time of 95 days in all the animals. The cortical bone allograft submitted to liquid nitrogen freezing provided adequate bone healing in the sheep model.
ISSN:0103-8478
DOI:10.1590/0103-8478cr20140006