Laparoscopic ureterocalicostomy in pigs--experimental study/Ureterocalicostomia laparoscopica em suinos--estudo experimental

• Published in: Ciência rural 2015-07, Vol.45 (7), p.1262
• Main Authors: Caldas, Paulo Fernando de Oliveira, Rocha, Luiz Carlos de Almeida, de Oliveira, Marilia Teresa, de Ataide, Michelli Westphal, Spagnolo, Julio David, Feranti, Joao Pedro Scussel, de Souza, Fernando Wiecheteck, Silva, Marco Augusto Machado, Brun, Mauricio Veloso
• Format: Article
• Language: Spanish
• ISSN: 0103-8478
• DOI: 10.1590/0103-8478cr20140384

This study aimed to evaluated laparoscopic ureterocalicostomy as treatment of experimental ureteropelvic junction (UPJ) obstruction in pigs. Ten male Large White pigs weighting approximately 28.4 (± 1.43) kg were used in the current study. The UPJ obstruction was created laparoscopically by double-clipping of the left ureter. After 14 days the animals underwent laparoscopic ureterocalicostomy f The animals were sacrificed for subsequent retrograde pyelography in order to assess the anastomotic patency on the 28th day. The laparoscopic procedure for experimental obstruction of UPJ was successfully performed in all animals, as well as the laparoscopic ureterocalicostomy. There was intestinal iatrogenic injury in one animal. Satisfactory UPJ patency was noted in 75% of the animals. There was no stenosis of the proximal anastomosis between the ureter and the lower pole of the kidney in 37.5%, mild stenosis in 37.5% and severe stenosis in 25% of the animals. The laparoscopic approach for reestablishment he urinary flow by ureterocalicostomy was feasible in the porcine model. The ascending pyelography revealed satisfactory results of the laparoscopic ureterocalicostomy. Key words: laparoscopy, urinary, constriction, nephrology, swine model. O estudo teve como objetivo avaliar a ureterocalicostomia laparoscopica no tratamento de obstrucao da juncao ureteropielica (JUP) em modelo experimental suino. Foram selecionados 10 suinos machos da raca Large White com peso medio de 28,4(± 1,43) kg. A obstrucao da JUP foi criada por tecnica laparoscopica transperitoneal, com aplicacao de dois clipes de titanio no ureter esquerdo. Passados 14 dias, os animais foram submetidos a ureterocalicostomia laparoscopica. No 28 dia apos a ureterocalicostomia, foram sacrificados para a remocao dos rins e posterior pielografia retrograda para avaliacao da permeabilidade anastomotica. A obstrucao da JUP foi obtida com sucesso em todos os animais, assim como a ureterocalicostomia laparoscopica, apesar de ter havido lesao intestinal em um dos animais. Boa permeabilidade foi observada em 75% dos casos, posteriormente a anastomose entre o ureter proximal e o calice maior caudal do rim, onde 37,5% dos animais nao apresentaram estenose, 37,5% apresentaram estenose leve, enquanto 25% apresentaram estenose severa. Foi possivel restabelecer o fluxo urinario por ureterocalicostomia laparoscopica e os resultados anatomicos obtidos por meio das pielografias ascendentes foram considerados satisfatorio