A stiff person case admitted phsysical medicine and rehabilitation outpatient clinic with low back pain/Bel agrisi sikayetiyle fiziksel tip ve rehabilitasyon poliklinigine basvuran bir stiff person sendromu olgusu

Stiff-Person Syndrome (SPS) is a rare disorder that is characterized by stiffness and rigidity of the axial, abdominal, and extremity muscles. It is associated with several autoimmune diseases or paraneoplastic conditions. We report a case of SPS with Hashimoto's thyroiditis who complained of l...

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Bibliographic Details
Published in:Türkiye fiziksel tip ve rehabilitasyon dergisi 2015-09, Vol.61 (3), p.272
Main Authors: Karaoglan, Belgin, Ote, Seyda, Koseoglu, Ebru, Balevi, Elif
Format: Article
Language:English
Subjects:
Analysis
Backache
Care and treatment
Clinics
Rehabilitation
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Summary:Stiff-Person Syndrome (SPS) is a rare disorder that is characterized by stiffness and rigidity of the axial, abdominal, and extremity muscles. It is associated with several autoimmune diseases or paraneoplastic conditions. We report a case of SPS with Hashimoto's thyroiditis who complained of low back pain. Her physical examination was remarkable in that her abdominal and axial muscles were firm to palpation, and she had hyperlordosis of the spine. Active range of motion of the spine was limited, and she had a robotic gait. Electromyography demonstrated continuous motor unit activity in the agonist and antagonist muscles. Diagnosis of SPS was confirmed because antiglutamic acid decarboxylase was present in the cerebrospinal fluid. She favorably responded to intravenous administration of immunoglobulin, diazepam, and baclofen and stretching, strengthening, and range of motion exercises. Keywords: Back pain, Hyperlordosis, Stiff-Person Syndrome Stiff Person Sendromu (SPS); aksiyel, abdominal ve ekstremite kaslarinda sertlik ve rijidite ile karakterize nadir gorulen bir hastaliktir. Bazi otoimmun hastaliklarla veya paraneoplastik sendromlarla iliskilidir. Biz, bel agrisiyla poliklinigimize basvuran Hashimoto tiroiditli bir SPS vakasi sunduk. Fizik muayenede abdominal ve aksiyel kaslarinda palpasyonla sertlik dikkat cekiciydi ve belirgin lomber hiperlordozu mevcuttu. Bel aktif eklem hareket acikligi kisitliydi ve robotik yuruyus paterni vardi. Yapilan elektromiyografi incelemesinde agonist ve antagonist kaslarda surekli motor unite aktivitesi izlendi. Beyin omurilik sivisinda anti-glutamik asit dekarboksilaz pozitifliginin gosterilmesiyle SPS tanisi dogrulandi. Hasta intravenoz immunglobulin, diazepam, baklofen ve germe, guclendirme, eklem hareket acikligi egzersizlerine olumlu cevap verdi. Anahtar Kelimeler: Bel agrisi, Hiperlordoz, Stiff Person Sendromu
ISSN:1302-0234
DOI:10.5152/tftrd.2015.57778