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Pancreatic [beta]-cell regeneration: advances in understanding the genes and signaling pathways involved

Editorial summary Recent advances in [beta]-cell regeneration in vivo are providing insights into the mechanisms involved in the conversion of distinct pancreatic cell lineages into [beta] cells. These mechanisms mostly involve reactivation of the gene encoding the pancreatic endocrine cell-specifyi...

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Bibliographic Details
Published in:Genome medicine 2017-05, Vol.9 (1)
Main Authors: Afelik, Solomon, Rovira, Meritxell
Format: Article
Language:English
Online Access:Get full text
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Summary:Editorial summary Recent advances in [beta]-cell regeneration in vivo are providing insights into the mechanisms involved in the conversion of distinct pancreatic cell lineages into [beta] cells. These mechanisms mostly involve reactivation of the gene encoding the pancreatic endocrine cell-specifying transcription factor neurogenin-3.
ISSN:1756-994X
1756-994X
DOI:10.1186/s13073-017-0437-x