An Extract of Lychnis chalcedonica as the Basis for Developing a Novel Ecdysteroid-Containing Formulation with Actoprotector Activity

A novel ecdysteroid-containing pharmaceutical substance – Lychnis chalcedonica extract – was developed. The phytoecdysteroid composition of the ethanolic extract was determined. Courses of intragastric administration of Lychnis chalcedonica extract (150 mg/kg) were accompanied by anabolic effects in...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2017-12, Vol.51 (9), p.800-805
Main Authors: Plotnikov, M. B., Zibareva, L. N., Vasil’ev, A. S., Aliev, O. I.
Format: Article
Language:English
Subjects:
Carbohydrate metabolism
Medicinal Plants
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Summary:A novel ecdysteroid-containing pharmaceutical substance – Lychnis chalcedonica extract – was developed. The phytoecdysteroid composition of the ethanolic extract was determined. Courses of intragastric administration of Lychnis chalcedonica extract (150 mg/kg) were accompanied by anabolic effects in both trained and untrained animals. The actoprotector properties of the Lychnis chalcedonica extract and improvements in carbohydrate metabolism on exhaustive physical exertion were seen only in trained animals. Lychnis chalcedonica extract is a pharmaceutical substance with potential for use as the basis for developing formulations with actoprotector activity.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-017-1696-y