An Extract of Lychnis chalcedonica as the Basis for Developing a Novel Ecdysteroid-Containing Formulation with Actoprotector Activity

A novel ecdysteroid-containing pharmaceutical substance – Lychnis chalcedonica extract – was developed. The phytoecdysteroid composition of the ethanolic extract was determined. Courses of intragastric administration of Lychnis chalcedonica extract (150 mg/kg) were accompanied by anabolic effects in...

Full description

Saved in:
Bibliographic Details
Published in:Pharmaceutical chemistry journal 2017-12, Vol.51 (9), p.800-805
Main Authors: Plotnikov, M. B., Zibareva, L. N., Vasil’ev, A. S., Aliev, O. I.
Format: Article
Language:English
Subjects:
Carbohydrate metabolism
Medicinal Plants
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c355t-25ba4dffdd10d5a50935c5f075e6046ad72c9eea4414ba6044e9cad786d501c3
cites cdi_FETCH-LOGICAL-c355t-25ba4dffdd10d5a50935c5f075e6046ad72c9eea4414ba6044e9cad786d501c3
container_end_page 805
container_issue 9
container_start_page 800
container_title Pharmaceutical chemistry journal
container_volume 51
creator Plotnikov, M. B.
Zibareva, L. N.
Vasil’ev, A. S.
Aliev, O. I.
description A novel ecdysteroid-containing pharmaceutical substance – Lychnis chalcedonica extract – was developed. The phytoecdysteroid composition of the ethanolic extract was determined. Courses of intragastric administration of Lychnis chalcedonica extract (150 mg/kg) were accompanied by anabolic effects in both trained and untrained animals. The actoprotector properties of the Lychnis chalcedonica extract and improvements in carbohydrate metabolism on exhaustive physical exertion were seen only in trained animals. Lychnis chalcedonica extract is a pharmaceutical substance with potential for use as the basis for developing formulations with actoprotector activity.
doi_str_mv 10.1007/s11094-017-1696-y
format article
fullrecord <record><control><sourceid>gale_cross</sourceid><recordid>TN_cdi_gale_infotracmisc_A517939692</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A517939692</galeid><sourcerecordid>A517939692</sourcerecordid><originalsourceid>FETCH-LOGICAL-c355t-25ba4dffdd10d5a50935c5f075e6046ad72c9eea4414ba6044e9cad786d501c3</originalsourceid><addsrcrecordid>eNp9kctKBDEQRYMoOD4-wF3AdbTS3ek2y3EcHzDoZhbuQsxjJtKTDEl89Af436YZN4JILYq6dU9BcRE6o3BBAbrLRCnwhgDtCG15S4Y9NKGsqwmHmu6jCQCnhDJ4PkRHKb0CFKquJuhr6vH8M0epMg4WLwa19i5htZa9Mjp4pySWCee1wdcylY0NEd-Yd9OHrfMrLPFjKAOeKz2kbGJwmsyCz9L5cX0b4uatl9kFjz9cXuOpymEbQzalx3Fy7y4PJ-jAyj6Z059-jJa38-Xsniye7h5m0wVRNWOZVOxFNtparSloJhnwmilmoWOmhaaVuqsUN0Y2DW1eZJEaw1VRr1rNgKr6GJ3vzq5kb4TzNoyPb1xSYspox2ve8qq4Lv5wldJm41Twxrqi_wLoDlAxpBSNFdvoNjIOgoIY0xG7dERJR4zpiKEw1Y5JxetXJorX8BZ9ef4f6BspWpSw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>An Extract of Lychnis chalcedonica as the Basis for Developing a Novel Ecdysteroid-Containing Formulation with Actoprotector Activity</title><source>Springer Link</source><creator>Plotnikov, M. B. ; Zibareva, L. N. ; Vasil’ev, A. S. ; Aliev, O. I.</creator><creatorcontrib>Plotnikov, M. B. ; Zibareva, L. N. ; Vasil’ev, A. S. ; Aliev, O. I.</creatorcontrib><description>A novel ecdysteroid-containing pharmaceutical substance – Lychnis chalcedonica extract – was developed. The phytoecdysteroid composition of the ethanolic extract was determined. Courses of intragastric administration of Lychnis chalcedonica extract (150 mg/kg) were accompanied by anabolic effects in both trained and untrained animals. The actoprotector properties of the Lychnis chalcedonica extract and improvements in carbohydrate metabolism on exhaustive physical exertion were seen only in trained animals. Lychnis chalcedonica extract is a pharmaceutical substance with potential for use as the basis for developing formulations with actoprotector activity.</description><identifier>ISSN: 0091-150X</identifier><identifier>EISSN: 1573-9031</identifier><identifier>DOI: 10.1007/s11094-017-1696-y</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Carbohydrate metabolism ; Medicinal Plants ; Medicine ; Organic Chemistry ; Pharmacology/Toxicology ; Pharmacy</subject><ispartof>Pharmaceutical chemistry journal, 2017-12, Vol.51 (9), p.800-805</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2017</rights><rights>COPYRIGHT 2017 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c355t-25ba4dffdd10d5a50935c5f075e6046ad72c9eea4414ba6044e9cad786d501c3</citedby><cites>FETCH-LOGICAL-c355t-25ba4dffdd10d5a50935c5f075e6046ad72c9eea4414ba6044e9cad786d501c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Plotnikov, M. B.</creatorcontrib><creatorcontrib>Zibareva, L. N.</creatorcontrib><creatorcontrib>Vasil’ev, A. S.</creatorcontrib><creatorcontrib>Aliev, O. I.</creatorcontrib><title>An Extract of Lychnis chalcedonica as the Basis for Developing a Novel Ecdysteroid-Containing Formulation with Actoprotector Activity</title><title>Pharmaceutical chemistry journal</title><addtitle>Pharm Chem J</addtitle><description>A novel ecdysteroid-containing pharmaceutical substance – Lychnis chalcedonica extract – was developed. The phytoecdysteroid composition of the ethanolic extract was determined. Courses of intragastric administration of Lychnis chalcedonica extract (150 mg/kg) were accompanied by anabolic effects in both trained and untrained animals. The actoprotector properties of the Lychnis chalcedonica extract and improvements in carbohydrate metabolism on exhaustive physical exertion were seen only in trained animals. Lychnis chalcedonica extract is a pharmaceutical substance with potential for use as the basis for developing formulations with actoprotector activity.</description><subject>Carbohydrate metabolism</subject><subject>Medicinal Plants</subject><subject>Medicine</subject><subject>Organic Chemistry</subject><subject>Pharmacology/Toxicology</subject><subject>Pharmacy</subject><issn>0091-150X</issn><issn>1573-9031</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp9kctKBDEQRYMoOD4-wF3AdbTS3ek2y3EcHzDoZhbuQsxjJtKTDEl89Af436YZN4JILYq6dU9BcRE6o3BBAbrLRCnwhgDtCG15S4Y9NKGsqwmHmu6jCQCnhDJ4PkRHKb0CFKquJuhr6vH8M0epMg4WLwa19i5htZa9Mjp4pySWCee1wdcylY0NEd-Yd9OHrfMrLPFjKAOeKz2kbGJwmsyCz9L5cX0b4uatl9kFjz9cXuOpymEbQzalx3Fy7y4PJ-jAyj6Z059-jJa38-Xsniye7h5m0wVRNWOZVOxFNtparSloJhnwmilmoWOmhaaVuqsUN0Y2DW1eZJEaw1VRr1rNgKr6GJ3vzq5kb4TzNoyPb1xSYspox2ve8qq4Lv5wldJm41Twxrqi_wLoDlAxpBSNFdvoNjIOgoIY0xG7dERJR4zpiKEw1Y5JxetXJorX8BZ9ef4f6BspWpSw</recordid><startdate>20171201</startdate><enddate>20171201</enddate><creator>Plotnikov, M. B.</creator><creator>Zibareva, L. N.</creator><creator>Vasil’ev, A. S.</creator><creator>Aliev, O. I.</creator><general>Springer US</general><general>Springer</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20171201</creationdate><title>An Extract of Lychnis chalcedonica as the Basis for Developing a Novel Ecdysteroid-Containing Formulation with Actoprotector Activity</title><author>Plotnikov, M. B. ; Zibareva, L. N. ; Vasil’ev, A. S. ; Aliev, O. I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c355t-25ba4dffdd10d5a50935c5f075e6046ad72c9eea4414ba6044e9cad786d501c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Carbohydrate metabolism</topic><topic>Medicinal Plants</topic><topic>Medicine</topic><topic>Organic Chemistry</topic><topic>Pharmacology/Toxicology</topic><topic>Pharmacy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Plotnikov, M. B.</creatorcontrib><creatorcontrib>Zibareva, L. N.</creatorcontrib><creatorcontrib>Vasil’ev, A. S.</creatorcontrib><creatorcontrib>Aliev, O. I.</creatorcontrib><collection>CrossRef</collection><jtitle>Pharmaceutical chemistry journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Plotnikov, M. B.</au><au>Zibareva, L. N.</au><au>Vasil’ev, A. S.</au><au>Aliev, O. I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Extract of Lychnis chalcedonica as the Basis for Developing a Novel Ecdysteroid-Containing Formulation with Actoprotector Activity</atitle><jtitle>Pharmaceutical chemistry journal</jtitle><stitle>Pharm Chem J</stitle><date>2017-12-01</date><risdate>2017</risdate><volume>51</volume><issue>9</issue><spage>800</spage><epage>805</epage><pages>800-805</pages><issn>0091-150X</issn><eissn>1573-9031</eissn><abstract>A novel ecdysteroid-containing pharmaceutical substance – Lychnis chalcedonica extract – was developed. The phytoecdysteroid composition of the ethanolic extract was determined. Courses of intragastric administration of Lychnis chalcedonica extract (150 mg/kg) were accompanied by anabolic effects in both trained and untrained animals. The actoprotector properties of the Lychnis chalcedonica extract and improvements in carbohydrate metabolism on exhaustive physical exertion were seen only in trained animals. Lychnis chalcedonica extract is a pharmaceutical substance with potential for use as the basis for developing formulations with actoprotector activity.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s11094-017-1696-y</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0091-150X
ispartof Pharmaceutical chemistry journal, 2017-12, Vol.51 (9), p.800-805
issn 0091-150X
1573-9031
language eng
recordid cdi_gale_infotracmisc_A517939692
source Springer Link
subjects Carbohydrate metabolism
Medicinal Plants
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
title An Extract of Lychnis chalcedonica as the Basis for Developing a Novel Ecdysteroid-Containing Formulation with Actoprotector Activity
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T13%3A38%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=An%20Extract%20of%20Lychnis%20chalcedonica%20as%20the%20Basis%20for%20Developing%20a%20Novel%20Ecdysteroid-Containing%20Formulation%20with%20Actoprotector%20Activity&rft.jtitle=Pharmaceutical%20chemistry%20journal&rft.au=Plotnikov,%20M.%20B.&rft.date=2017-12-01&rft.volume=51&rft.issue=9&rft.spage=800&rft.epage=805&rft.pages=800-805&rft.issn=0091-150X&rft.eissn=1573-9031&rft_id=info:doi/10.1007/s11094-017-1696-y&rft_dat=%3Cgale_cross%3EA517939692%3C/gale_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c355t-25ba4dffdd10d5a50935c5f075e6046ad72c9eea4414ba6044e9cad786d501c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rft_galeid=A517939692&rfr_iscdi=true