Simultaneous determination of salidroside, rosavin, and rosarin in extracts from Rhodiola rosea by high performance liquid chromatography with tandem mass spectrometry detection

s An approach is developed for the simultaneous determination of salidroside, rosarin, and rosavin in extracts from plant based on liquid chromatography/mass spectrometry; the detection limits of the method are 2, 4, and 6 ng/mL for salidroside, rosavin, and rosarin, respectively. The method was val...

Full description

Saved in:
Bibliographic Details
Published in:Journal of analytical chemistry (New York, N.Y.) N.Y.), 2012-12, Vol.67 (13), p.1026-1030
Main Authors: Rodin, I. A., Stavrianidi, A. N., Braun, A. V., Shpigun, O. A., Popik, M. V.
Format: Article
Language:English
Subjects:
Analysis
Analytical Chemistry
Chemical properties
Chemistry
Chemistry and Materials Science
Composition
Crassulaceae
Glycosides
High performance liquid chromatography
Identification and classification
Mass spectrometry
Materia medica, Vegetable
Methods
Physiological aspects
Plant extracts
Spectroscopy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:s An approach is developed for the simultaneous determination of salidroside, rosarin, and rosavin in extracts from plant based on liquid chromatography/mass spectrometry; the detection limits of the method are 2, 4, and 6 ng/mL for salidroside, rosavin, and rosarin, respectively. The method was validated using real extracts from Rhodiola rosea rhizome. The analysis of extracts was accomplished by reversed-phase chromatography with a SB-C18 stationary phase. The analytes were detected by tandem mass spectrometry with electrospray ionization in the multiple reaction monitoring mode for negative ions.
ISSN:1061-9348
1608-3199
DOI:10.1134/S1061934812130096