Synthesis and Biological Activity of Several Modified 5[alpha]-Androstanolone Derivatives

Several new N-containing epiandrosterone derivatives modified by phenylacetic acid chloride were synthesized for biological activity studies. Compounds with antiviral activity were discovered among them and 3[beta]-hydroxy-1'-aryl-3'-methyl-5'-androstano[17,16-d]pyrazolines prepared b...

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Bibliographic Details
Published in:Chemistry of natural compounds 2018-03, Vol.54 (2), p.310
Main Authors: Nadaraia, N. Sh, Barbakadze, N. N, Kakhabrishvili, M. L, Sylla, B, Pichette, A, Makhmudov, U. S
Format: Article
Language:English
Subjects:
Antiviral agents
Phenylacetic acid
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Summary:Several new N-containing epiandrosterone derivatives modified by phenylacetic acid chloride were synthesized for biological activity studies. Compounds with antiviral activity were discovered among them and 3[beta]-hydroxy-1'-aryl-3'-methyl-5'-androstano[17,16-d]pyrazolines prepared by us earlier.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-018-2330-2