Course of Neuropsychiatrie Symptoms during Flares of Systemic Lupus Erythematosus

We present the case of a seventeen-year-old girl who presents with an interesting course of neuropsychiatric symptoms during several flares of SLE. The patient was diagnosed at the age of thirteen and has had four flares in total. The latter two flares included cutaneous and neuropsychiatric symptom...

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Bibliographic Details
Published in:Case reports in psychiatry 2017-01, Vol.2017
Main Authors: Garrett, Gareth, Ambrose, Nicola, Davids, Zaib, Bindman, Dorothea
Format: Article
Language:English
Subjects:
Diagnosis
Lupus
Olanzapine
Systemic lupus erythematosus
Teenage girls
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Summary:We present the case of a seventeen-year-old girl who presents with an interesting course of neuropsychiatric symptoms during several flares of SLE. The patient was diagnosed at the age of thirteen and has had four flares in total. The latter two flares included cutaneous and neuropsychiatric symptoms. The most recent flare occurred when she was aged seventeen. She had cutaneous symptoms which coincided with an episode of hypomania. Her mental state further deteriorated following steroid treatment. She exhibited affective and psychotic symptoms. Treatment with cyclophosphamide and olanzapine was associated with an improvement in both cutaneous and neuropsychiatric symptoms. Previously aged sixteen the patient had presented with cutaneous symptoms and a moderate depressive episode which was also exacerbated by steroid treatment. The patient's mood improved when the dose of oral steroids was reduced to a daily dose of 15-20 mg prednisolone.
ISSN:2090-682X
DOI:10.1155/2017/2890436