Utility of [[sup.18]F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan in Inflammatory Myopathies: Case Report and Literature Review

Introduction. Inflammatory myopathies are a rare group of diseases characterized by proximal weakness. Incidence ranges from 7.98/million/year and prevalence at 14/100,000. The utility of [[sup.18]F] fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) scan is increas...

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Bibliographic Details
Published in:Case reports in rheumatology 2018-01, Vol.2018
Main Authors: Noriega, Juan Pablo Rivas-de, Galnares-Olalde, Javier Andres, Zuniga-Varga, Javier, Herrera-Felix, Juan Pablo, Alegria- Loyola, Marco Antonio, Turrent-Carriles, Alonso
Format: Article
Language:English
Subjects:
Creatine
Creatine kinase
CT imaging
PET imaging
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Summary:Introduction. Inflammatory myopathies are a rare group of diseases characterized by proximal weakness. Incidence ranges from 7.98/million/year and prevalence at 14/100,000. The utility of [[sup.18]F] fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) scan is increasing for the complementary diagnosis of myopathies. Case Report. An 84- year-old male was admitted with a history of difficulty rising from a chair and a fall. Laboratory results showed increased creatine kinase levels of more than 50 times the normal reference values. Electromyography (EMG) showed myopathic changes, and FDGPET/CT scan showed increased FDG uptake in bilateral quadriceps. A biopsy was performed revealing lymphocytic predominant infiltrates and myonecrosis. Prednisone and intravenous immunoglobulin (IVIG) were administered with strength improvement. The patient was discharged for further follow-up. Discussion. FDG-PET/CT in inflammatory diseases has proven useful as muscle fibers have increased FDG uptake. In some cases, FDG-PET/CT is also useful in determining associated neoplastic diseases.
ISSN:2090-6889
DOI:10.1155/2018/8398453