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Hypovitaminosis D in Hepatitis C patients and its relation with demographic and laboratory data

To determine the frequency of vitamin-D deficiency in hepatitis C patients and its relation with demographic and baseline laboratory data. The cross-sectional study was conducted at the University Institute of Medical Laboratory Technology, Faculty of Allied Health Sciences, The University of Lahore...

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Published in:	Journal of the Pakistan Medical Association 2019-11, Vol.69 (11), p.1637-1641
Main Authors:	Jafar, Junaid, Junaid, Kashaf, Saleem, Khurram, Amjed, Sameen, Arshad, Fatima, Amjed, Tuaha, Raja, Nazarullah, Gillani, Amir
Format:	Article
Language:	English
Subjects:	Adolescent Adult Anemia Anopheles Cross-Sectional Studies Developing countries EDTA Female Health aspects Hepatitis C - blood Hepatitis C - complications Hepatitis C - epidemiology Hepatitis C - virology Hepatitis C virus Humans Infection Male Medical research Middle Aged Pakistan - epidemiology Viral Load Vitamin D Vitamin D deficiency Vitamin D Deficiency - complications Vitamin D Deficiency - epidemiology Vitamins Young Adult
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container_issue	11
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container_title	Journal of the Pakistan Medical Association
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creator	Jafar, Junaid Junaid, Kashaf Saleem, Khurram Amjed, Sameen Arshad, Fatima Amjed, Tuaha Raja, Nazarullah Gillani, Amir
description	To determine the frequency of vitamin-D deficiency in hepatitis C patients and its relation with demographic and baseline laboratory data. The cross-sectional study was conducted at the University Institute of Medical Laboratory Technology, Faculty of Allied Health Sciences, The University of Lahore, Pakistan, from April 3 to July 24, 2017, and comprised diagnosed hepatitis C genotype 3 patients aged 18-60 years. Demographic data was collected on a predesigned proforma. Tests included complete blood counts, liver function test, hepatitis C viral load and 25-hydroxy Vitamin-D level. Data was analysed using SPSS 24. Of the 115 patients, 54(47%) were male and 61(53%) were females. Mean vitamin-D level was 22.3±11.3. Total 25(21.7%) patients showed normal level of vitamin-D while the level was low in 90(78.3%) patients; 41(35.6%) showed vitamin-D insufficiency and 49(42.6%) vitamin-D deficiency. Significant effect of sun exposure was recorded on patient's vitamin-D level (p=0.00). Significantly low hepatitis C viral load was seen in patients with normal vitamin-D (p= 0. 02 6 ). Patients with hepatitis C virus infection had high incidence of hypo-vitaminosis D.
doi_str_mv	10.5455/JPMA.301067.
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The cross-sectional study was conducted at the University Institute of Medical Laboratory Technology, Faculty of Allied Health Sciences, The University of Lahore, Pakistan, from April 3 to July 24, 2017, and comprised diagnosed hepatitis C genotype 3 patients aged 18-60 years. Demographic data was collected on a predesigned proforma. Tests included complete blood counts, liver function test, hepatitis C viral load and 25-hydroxy Vitamin-D level. Data was analysed using SPSS 24. Of the 115 patients, 54(47%) were male and 61(53%) were females. Mean vitamin-D level was 22.3±11.3. Total 25(21.7%) patients showed normal level of vitamin-D while the level was low in 90(78.3%) patients; 41(35.6%) showed vitamin-D insufficiency and 49(42.6%) vitamin-D deficiency. Significant effect of sun exposure was recorded on patient's vitamin-D level (p=0.00). Significantly low hepatitis C viral load was seen in patients with normal vitamin-D (p= 0. 02 6 ). Patients with hepatitis C virus infection had high incidence of hypo-vitaminosis D.</description><identifier>ISSN: 0030-9982</identifier><identifier>DOI: 10.5455/JPMA.301067.</identifier><identifier>PMID: 31740870</identifier><language>eng</language><publisher>Pakistan: Knowledge Bylanes</publisher><subject>Adolescent ; Adult ; Anemia ; Anopheles ; Cross-Sectional Studies ; Developing countries ; EDTA ; Female ; Health aspects ; Hepatitis C - blood ; Hepatitis C - complications ; Hepatitis C - epidemiology ; Hepatitis C - virology ; Hepatitis C virus ; Humans ; Infection ; Male ; Medical research ; Middle Aged ; Pakistan - epidemiology ; Viral Load ; Vitamin D ; Vitamin D deficiency ; Vitamin D Deficiency - complications ; Vitamin D Deficiency - epidemiology ; Vitamins ; Young Adult</subject><ispartof>Journal of the Pakistan Medical Association, 2019-11, Vol.69 (11), p.1637-1641</ispartof><rights>COPYRIGHT 2019 Knowledge Bylanes</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31740870$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jafar, Junaid</creatorcontrib><creatorcontrib>Junaid, Kashaf</creatorcontrib><creatorcontrib>Saleem, Khurram</creatorcontrib><creatorcontrib>Amjed, Sameen</creatorcontrib><creatorcontrib>Arshad, Fatima</creatorcontrib><creatorcontrib>Amjed, Tuaha</creatorcontrib><creatorcontrib>Raja, Nazarullah</creatorcontrib><creatorcontrib>Gillani, Amir</creatorcontrib><title>Hypovitaminosis D in Hepatitis C patients and its relation with demographic and laboratory data</title><title>Journal of the Pakistan Medical Association</title><addtitle>J Pak Med Assoc</addtitle><description>To determine the frequency of vitamin-D deficiency in hepatitis C patients and its relation with demographic and baseline laboratory data. The cross-sectional study was conducted at the University Institute of Medical Laboratory Technology, Faculty of Allied Health Sciences, The University of Lahore, Pakistan, from April 3 to July 24, 2017, and comprised diagnosed hepatitis C genotype 3 patients aged 18-60 years. Demographic data was collected on a predesigned proforma. Tests included complete blood counts, liver function test, hepatitis C viral load and 25-hydroxy Vitamin-D level. Data was analysed using SPSS 24. Of the 115 patients, 54(47%) were male and 61(53%) were females. Mean vitamin-D level was 22.3±11.3. Total 25(21.7%) patients showed normal level of vitamin-D while the level was low in 90(78.3%) patients; 41(35.6%) showed vitamin-D insufficiency and 49(42.6%) vitamin-D deficiency. Significant effect of sun exposure was recorded on patient's vitamin-D level (p=0.00). Significantly low hepatitis C viral load was seen in patients with normal vitamin-D (p= 0. 02 6 ). 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subjects	Adolescent Adult Anemia Anopheles Cross-Sectional Studies Developing countries EDTA Female Health aspects Hepatitis C - blood Hepatitis C - complications Hepatitis C - epidemiology Hepatitis C - virology Hepatitis C virus Humans Infection Male Medical research Middle Aged Pakistan - epidemiology Viral Load Vitamin D Vitamin D deficiency Vitamin D Deficiency - complications Vitamin D Deficiency - epidemiology Vitamins Young Adult
title	Hypovitaminosis D in Hepatitis C patients and its relation with demographic and laboratory data
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