RADIOTHERAPY OF PROSTATE CANCER: PRIMARY RADIOTHERAPY AND RADIOTHERAPY IN DISEASE RELAPSE/RADIOTERAPIJA RAKA PROSTATE : PRIMARNA RADIOTERAPIJA I RADIOTERAPIJA U POVRATU BOLESTI

Radiotherapy presents one of the essential modes of treatment in patients with prostate cancer at almost any stage of the disease. It can be delivered as external beam radiotherapy, as brachytherapy or two methods combined. Higher radiation doses are proven to be more effective than low doses and mo...

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Bibliographic Details
Published in:Acta clinica Croatica (Tisak) 2019-11, Vol.58 (S2), p.46
Main Author: Antunac, Katarina
Format: Article
Language:English
Subjects:
Brachytherapy
Cancer patients
Care and treatment
Diseases
Prostate cancer
Radiotherapy
Recurrence (Disease)
Resveratrol
Setting (Literature)
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Summary:Radiotherapy presents one of the essential modes of treatment in patients with prostate cancer at almost any stage of the disease. It can be delivered as external beam radiotherapy, as brachytherapy or two methods combined. Higher radiation doses are proven to be more effective than low doses and moderate hypofractionation with doses up to 3.4 Gy per fraction is proven equivalent to standard fractionation using 1.8-2 Gy per fraction. Stereotactic body radiotherapy (SBRT) with doses from 3.4 to 7.25 Gy per fraction presents valuable option in certain subgroups of patients. In case of local regional disease relapse, radiotherapy is used in curative setting. Key words: prostate cancer, radiotherapy, brachytherapy, hypofractionation, stereotactic body radiotherapy, salvage radiotherapy Radioterapija predstavlja jedan od osnovnih modaliteta lijecenja bolesnika s rakom prostate u gotovo svim stadijima bolesti. Može se koristiti kao vanjsko zracenje, kao brahiterapija (unutarnje zracenje) ili kombinacija ove dvije metode. Više doze zracenja su dokazano ucinkovitije od nižih a umjereno hipofrakcionirano zracenje dozama do 3,4 Gy po frakciji je jednako ucinkovito kao i zracenje standardnim frakcioniranjem od 1,8-2 Gy po frakciji. Stereotaksijsko zracenje dozama od 3, 4 do 7, 25 Gy po frakciji predstavlja vrijednu opciju kod odredenih podskupina bolesnika. U slucaju lokoregionalnog povrata bolesti, zracenje se može provoditi s ciljem izljecenja bolesnika. Kljucne rijeci: rak prostate, radioterapija, brahiterapija, hipofrakcioniranje, stereotaksijsko zracenje, spasonosna radioterapija
ISSN:0353-9466
DOI:10.20471/acc.2019.58.s2.08