Induction of labor with oxytocin in pregnancy with low-risk heart disease: A randomized controlled trial/Dusuk riskli kalp hastaligi olan gebelerde oksitosin ile dogum induksiyonu: Randomize kontrollu bir calisma

• Published in: Turkish journal of obstetrics and gynecology 2019-12, Vol.16 (4), p.213
• Main Authors: Dogra, Yogita, Suri, Vanita, Aggarwal, Neelam, Dogra, Ravi Kant
• Format: Article
• Language: English
• Subjects: Cardiac patients; Cardiovascular diseases; Comparative analysis; Delivery (Childbirth); Diseases; Infant mortality; Infection control; Newborn infants; Obstetrics; Pregnancy; Pregnant women; Risk factors; Women
• ISSN: 2149-9322
• DOI: 10.4274/tjod.galenos.2019.59932

Objective: To compare maternal and perinatal outcomes in pregnant women with underlying heart disease who underwent induction of labor with those who had spontaneous labor. Materials and Methods: A total of 50 pregnant women with heart disease who were registered in cardio-obstetric clinic were recruited consecutively between 38-41 weeks' gestation. Patients with favorable Bishop scores at 38 weeks were randomized into two groups. Induction of labor with oxytocin was performed in one group, and the second group underwent spontaneous onset of labor. Descriptive analysis in terms of mean, standard deviation, and percentage was performed. Unpaired t-test was applied for comparison of two groups using SPPS statistical software. Results: No significant difference in the rate of maternal complications was observed between the two groups. No cardiac complications were reported in pregnant females who underwent induction of labor. Fifty-two percent of patients delivered during workday hours when labor was induced, whereas only 24% of pregnant women delivered during working hours who underwent spontaneous delivery. No maternal or neonatal deaths were reported. Conclusion: Induction of labor with oxytocin is a relatively safe procedure in women with heart disease, it does not result in any cardiac complications. More patients delivered during daytime when electively induced, which minimized the maternal and fetal risks because obstetric, anesthesiologist, cardiologist, and perinatologist specialists are readily available during the daytime. Keywords: Heart disease, labor, induction, caesarean, delivery Amac: Altta yatan kalp hastaligi olup, dogum induksiyonu gecirenlerde ve spontan dogum yapan gebelerde maternal ve perinatal ciktilari karsilastirmaktir. Gerec ve Yontemler: Kardiyo-obstetrik klinigine kayitli, kalp hastaligi olan, 38-41 hafta arasi gebelik donemindeki toplam 50 kadin art arda degerlendirildi. Otuz sekizinci haftada Bishop skorlari uygun olan hastalar iki gruba randomize edildi. Birinci grupta oksitosin ile dogum induksiyonu gerceklestirilirken, ikinci gruba spontan baslangicli dogum yapildi. Ortalama, standart sapma ve yuzde cinsinden tanimlayici analiz yapildi. SPSS istatistik yazilimi kullanilarak iki grubun karsilastirilmasinda eslesmemis t-testi uygulandi. Bulgular: Iki grup arasinda maternal komplikasyon oranlarinda anlamli farklilik gozlenmemistir. Dogum induksiyonu yapilan gebe kadinlarda kardiyak komplikasyonlar bildirilmemistir. Hastalarin %