Antimycotic Activity of Naftifine Hydrochloride Solution in Combination with Poly(Ethylene Glycols)

The microbiological activity of naftifine hydrochloride solution in combination with poly(ethylene glycols) (PEG-400 and PEG-1000) was determined and compared with that of the existing foreign drug Exoderil ® . The results showed that the fungistatic activity (minimum inhibitory concentration) of th...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2020-06, Vol.54 (3), p.310-311
Main Authors: Kosenkova, S. I., Krasnyuk, I. I., Krasnyuk Jr, I. I., Belyatskaya, A. V., Stepanova, O. I., Li, T., Fateeva, T. V., Mazyarkin, E. V., Novikov, V. V., Korochkina, T. V.
Format: Article
Language:English
Subjects:
Drug Synthesis Methods and Manufacturing Technology
Glycols
Medicine
Medicine, Botanic
Medicine, Herbal
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Summary:The microbiological activity of naftifine hydrochloride solution in combination with poly(ethylene glycols) (PEG-400 and PEG-1000) was determined and compared with that of the existing foreign drug Exoderil ® . The results showed that the fungistatic activity (minimum inhibitory concentration) of the proposed solution was about double that of Exoderil solution for Candida albicans ATCC 10231.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-020-02196-w