Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia

Purpose: The purpose of this study is the motor outcome analysis of early Botulinum toxin (BT) treatment in patients affected by large-angle infantile esotropia (IE). Patients and Methods: Retrospective analysis of 130 medical charts of IE patients who underwent BT injections between 2004 and 2019 w...

Full description

Saved in:
Bibliographic Details
Published in:Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2020-10, Vol.14, p.3399
Main Authors: Gallo, Flavio Gioele, Plaitano, Carmen, Veneruso, Paolo Esposito, Magli, Adriano
Format: Article
Language:English
Subjects:
Analysis
Botulinum toxins
Care and treatment
Childhood vision disorders
Esotropia
Medical research
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose: The purpose of this study is the motor outcome analysis of early Botulinum toxin (BT) treatment in patients affected by large-angle infantile esotropia (IE). Patients and Methods: Retrospective analysis of 130 medical charts of IE patients who underwent BT injections between 2004 and 2019 was performed. All patients underwent BT injections within 13 months of age. Results: Thirty patients, matching the inclusion criteria, were included in the study. Twenty-eight patients showing residual ET [greater than or equal to]25 PD (34.3[+ or -]6.6 PD ranged from 25 to 50) underwent surgery. Conclusion: Our result after 1 Botulinum toxin injection showed a very low success rate (6.7%) at last follow-up (28.3[+ or -]7.2 months). Our data would suggest one Botulinum toxin injection in children affected by large-angle infantile esotropia allows a significant reduction of deviation but does not avoid the need for surgical treatment. Keywords: strabismus, pediatric, congenital
ISSN:1177-5483
DOI:10.2l47/OPTH.S266652