Size-Exclusion Chromatography as a Technique for the Investigation of Novel Extracellular Vesicles in Cancer

Extracellular vesicles (EVs) are small particles that are released by cancer cells, and they may hold vital information for researchers looking for early markers for diagnosis. Size-exclusion chromatography (SEC) is a classical technique that has become increasingly popular and can be used for rapid...

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Bibliographic Details
Published in:Cancers 2020, Vol.12 (11), p.1
Main Authors: Liu, Daniel S.K, Upton, Flora M, Rees, Eleanor, Limb, Christopher, Jiao, Long R, Krell, Jonathan, Frampton, Adam E
Format: Report
Language:English
Subjects:
Cancer
Diagnosis
Gel permeation chromatography
Methods
Online Access:Get full text
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Summary:Extracellular vesicles (EVs) are small particles that are released by cancer cells, and they may hold vital information for researchers looking for early markers for diagnosis. Size-exclusion chromatography (SEC) is a classical technique that has become increasingly popular and can be used for rapid isolation and investigation of both their cargo and functionality. This systematic review highlights its main technical aspects, the type of materials involved and by covering the findings of the identified papers hopes to demonstrate the utility of this method in cancer research to date.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers12113156