Size-Exclusion Chromatography as a Technique for the Investigation of Novel Extracellular Vesicles in Cancer

Extracellular vesicles (EVs) are small particles that are released by cancer cells, and they may hold vital information for researchers looking for early markers for diagnosis. Size-exclusion chromatography (SEC) is a classical technique that has become increasingly popular and can be used for rapid...

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Published in:Cancers 2020, Vol.12 (11), p.1
Main Authors: Liu, Daniel S.K, Upton, Flora M, Rees, Eleanor, Limb, Christopher, Jiao, Long R, Krell, Jonathan, Frampton, Adam E
Format: Report
Language:English
Subjects:
Cancer
Diagnosis
Gel permeation chromatography
Methods
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container_issue 11
container_start_page 1
container_title Cancers
container_volume 12
creator Liu, Daniel S.K
Upton, Flora M
Rees, Eleanor
Limb, Christopher
Jiao, Long R
Krell, Jonathan
Frampton, Adam E
description Extracellular vesicles (EVs) are small particles that are released by cancer cells, and they may hold vital information for researchers looking for early markers for diagnosis. Size-exclusion chromatography (SEC) is a classical technique that has become increasingly popular and can be used for rapid isolation and investigation of both their cargo and functionality. This systematic review highlights its main technical aspects, the type of materials involved and by covering the findings of the identified papers hopes to demonstrate the utility of this method in cancer research to date.
doi_str_mv 10.3390/cancers12113156
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source Publicly Available Content (ProQuest); PubMed Central
subjects Cancer
Diagnosis
Gel permeation chromatography
Methods
title Size-Exclusion Chromatography as a Technique for the Investigation of Novel Extracellular Vesicles in Cancer
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