The Clinical Value of Klotho and FGF23 in Cardiac Valve Calcification Among Patients with Chronic Kidney Disease

Objective: This study aims to investigate the clinical value of serum Klotho and FGF23 in cardiac valve calcification in patients with chronic kidney disease (CKD). Methods: In the present study, 180 patients with CKD, who were admitted to the department of nephrology of our hospital on April 1, 201...

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Bibliographic Details
Published in:International journal of general medicine 2021-03, Vol.14, p.857
Main Authors: Chen, Yan, Chen, Yan-Xia, Huang, Chong, Duan, Zhi-Bing, Xu, Cheng-Yun
Format: Article
Language:English
Subjects:
Albumin
Calcification
Chronic kidney failure
Development and progression
Heart valve diseases
Hemoglobin
Medical research
Medicine, Experimental
Risk factors
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Summary:Objective: This study aims to investigate the clinical value of serum Klotho and FGF23 in cardiac valve calcification in patients with chronic kidney disease (CKD). Methods: In the present study, 180 patients with CKD, who were admitted to the department of nephrology of our hospital on April 1, 2016 (solstice, 2019), were selected as the main subjects. According to the CKD stage, these patients were divided into three groups: CKD2-3 group, CKD4 group, and CKD5 group. In each group, ultrasound was used to evaluate the cardiac valve calcification, and the independent risk factors for cardiac valve calcification were analyzed by Logistic regression. Results: The levels of hemoglobin and blood calcium in CKD2-3 patients were higher than those in CKD4 and CKD5 patients, and the levels of hemoglobin and blood calcium in CKD5 patients were higher than those in CKD4 patients (P
ISSN:1178-7074
1178-7074
DOI:10.2l47/IJGM.S299l97