C-reactive Protein to Albumin Ratio as a Prognostic Predictor in Larynx Cancer/Larinks Kanserinde Prognostik Bir Belirtec Olarak C-reaktif Protein Albumin Orani

Objective: During the past decade, several inflammation-based prognostic systems have been reported in the field of clinical oncology. Recently, C-reactive protein and albumin ratio (CAR) have showed their impact on a large variety of tumor types. The aim of this study is to evaluate the impact CAR...

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Bibliographic Details
Published in:Bagcilar Medical Bulletin 2020-12, Vol.5 (4), p.179
Main Authors: Cengiz, Abdurrahman Bugra, Gumuslu, Bekir Can, Kayabasi, Serkan, Tansuker, Hasan Deniz, Ogreden, Sahin, Oktay, Mehmet Faruk
Format: Article
Language:English
Subjects:
Albumin
C-reactive protein
Prognosis
Squamous cell carcinoma
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Summary:Objective: During the past decade, several inflammation-based prognostic systems have been reported in the field of clinical oncology. Recently, C-reactive protein and albumin ratio (CAR) have showed their impact on a large variety of tumor types. The aim of this study is to evaluate the impact CAR on prognosis and 5-year survival (5yS) in patients operated for larynx cancer. Method: One hundred eighteen patients operated in our center between 2010 and 2015 were eligible for retrospective analysis. We evaluated the impact of the CAR and neutrophil to lymphocyte ratio (NLR) on the 5yS. Univariate and multivariate Cox regression analyses were performed to determine the associations of CAR. Results: The optimal cut-off level of CAR was at 0.993. A low and high CAR was assigned to 40.7% and 59.3% of patients, respectively. The 5yS rates of patients with a high CAR were worse than those in the low group (79.2% vs 73.2% p
ISSN:2547-9431
2547-9431
DOI:10.4274/BMB.galenos.2020.07.032