Contribution of Endorectal Ultrasound, Magnetic Resonance Imaging and Positron Emission Tomography to Operation Strategy in Rectal Cancer/ Endorektal Ultrasonografi, Manyetik Rezonans Goruntuleme ve Pozitron Emisyon Tomografisinin Rektum Kanserinde Ameliyat Stratejisine Katkilari

• Published in: Bagcilar Medical Bulletin 2021-03, Vol.6 (1), p.61
• Main Authors: Firat, Yurdakul Deniz, Cipe, Gokhan, Cakir, Coskun, Bektasoglu, Huseyin Kazim, Arici, Sinan, Muslumanoglu, Mahmut
• Format: Article
• Language: English
• Subjects: Colorectal cancer; Comparative analysis; Diagnostic imaging; Gastrointestinal system; Homeopathy; Liver; Materia medica and therapeutics; Medical research; Medicine, Experimental; Metastasis; Therapeutics; Tomography; Ultrasound imaging
• ISSN: 2547-9431; 2547-9431
• DOI: 10.4274/BMB.galenos.2020.08.045

Objective: Colorectal cancer is the most common type of cancer in the gastrointestinal tract. Preoperative staging is important for applying appropriate treatment modalities. The role of endorectal ultrasonography (ERUS), magnetic resonance imaging (MRI) and positron emission-computed tomography (PET-CT) in rectal cancer patients was evaluated. Method: In this study, between October 2010-April 2012, 30 patients who were diagnosed as rectal cancer clinically and histopathologically were evaluated with ERUS, MRI and PET-CT preoperatively and results were compared with histopathologic findings. Results: Between October 2010-April 2012, 30 patients who were diagnosed as rectal cancer with biopsy in Bezmialem University Medical Faculty Hospital General Surgery Department were included in this study [20 male (66.6%), 10 female (33.3%) and their ages are 38-75 years old, 21 of them received neoadjuvant treatment and 9 of them did not received]. All patients were evaluated with MRI, ERUS and PETCT preoperatively. Rectal cancer patients who are primarily operated from rectal adenocarcinoma were included in this study. For T staging, preoperative MRI, ERUS and PET-CT staged 9 (31%), 12 (41%) and 12 (40%) of 30 patients accurately, respectively. For N staging, preoperative MRI, ERUS and PET-CT staged 15 (51%), 16 (55.1%) and 17 (56.6%) of 30 patients accurately, respectively. In comparison to other modalities, PET-CT did not yield a significant difference in staging and did not change operation strategy. PET-CT detected distant metastasis in 3 patients. One of them was liver and two of them were lung metastasis. Biopsies from mass predicted as lung metastasis did not result as metastasis. PET-CT has high rates of false positivity to detect distant metastasis. In statistical analysis, significant p-values for evaluation could not be obtained. Conclusion: Efficacy of routine use of PET-CT on staging, evaluation of T, N and extramesorectal spread could not be shown. Keywords: Imaging methods, PET-CT, rectum cancer Amac:Gastrointestinal sistemin en sik gorulen kanserleri kolorektal kanserlerdir. Ozellikle rektum kanserli hastalarda operasyon oncesi evreleme buyuk onem tasimaktador. Bunun sebebi ise evrelemeye gore tedavi yonetimindeki degisik olanaklarin hasta icin tercih edilebilmesidir. Evreleme hasta icin uygun tedavi yonetimini planlamaya yardimci olmaktadir. Rektum kanserli hastalarin endorektal ultrasonografi (ERUS), manyetik rezonans goruntuleme (MRG) ve pozitron