Phytochemical Analysis of Polyphenol Secondary Metabolites in Cloudberry (Rubus Chamaemorus L.) Leaves

Phytochemical analysis of cloudberry leaves isolated one new ( 1 ) and four well-known compounds ( 2 - 5 ) and established their structures. Compounds 1 (4- O -α- L -arabinofuranosylellagic acid) and 2 [(–)-epicatechin] belonged to the tannin class. The rest of the isolated compounds were the flavon...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2021-06, Vol.55 (3), p.253-258
Main Authors: Whaley, A. K., Ponkratova, A. O., Orlova, A. A., Serebryakov, E. B., Smirnov, S. N., Proksh, P., Ionov, N. S., Poroikov, V. V., Luzhanin, V. G.
Format: Article
Language:English
Subjects:
Bioflavonoids
Flavones
Flavonoids
Medicinal Plants
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Plant metabolites
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Summary:Phytochemical analysis of cloudberry leaves isolated one new ( 1 ) and four well-known compounds ( 2 - 5 ) and established their structures. Compounds 1 (4- O -α- L -arabinofuranosylellagic acid) and 2 [(–)-epicatechin] belonged to the tannin class. The rest of the isolated compounds were the flavonoid glucuronic glycosides quercetin 3- O -β- D -glucuronide ( 3 ), quercetin 3- O -β- D -2′′-galloylglucuronide ( 4 ), and kaempferol 3- O -β- D -glucuronide ( 5 ). Compounds 4 and 5 were isolated from Rubus chamaemorus L. for the first time. Predictions of the biological activity spectra for isolated 1 - 5 using the PASS program provided insights regarding the most promising directions for studying their biological activity.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-021-02407-y