Ion Chromatography for Small Molecule Determination in Clinical and Pharmaceutical Studies

In clinical and pharmaceutical research, the application of reliable, reproducible, and the best-available analytical methods and techniques are necessary because the quality of analysis may have a crucial effect on the health and life of patients. The role of inorganic and organic ions, as well as...

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Bibliographic Details
Published in:LCGC Asia pacific 2020-02, Vol.23 (1), p.6
Main Authors: Michalski, Rajmund, Blazewicz, Anna, Konczyk, Joanna, Krupa, Katarzyna, Nizinski, Przemyslaw
Format: Article
Language:English
Subjects:
Chromatography
Health aspects
Online Access:Get full text
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Summary:In clinical and pharmaceutical research, the application of reliable, reproducible, and the best-available analytical methods and techniques are necessary because the quality of analysis may have a crucial effect on the health and life of patients. The role of inorganic and organic ions, as well as ionizable substances, is very important for health. A very useful instrumental method for this range is ion chromatography (IC) and related techniques. Various ion chromatography methods are used in clinical and pharmaceutical research mainly to determine inorganic anions and cations, metals and metalloids, as well as selected organic compounds. This article presents possible uses of ion chromatography and related techniques combined with various detection methods for clinical and pharmaceutical analysis of common inorganic and organic anions and cations. An overview of achievements in this area from the past 10 years is presented and the most important trends and development perspectives for ion chromatography are described.
ISSN:1754-2715
1754-2715