Comparison of Antibacterial Effect of Probiotic Yogurt and Xylitol-Containing Chewing Gum in Geriatric Patients: A Randomized Controlled Clinical Trial /Usporedba antibakterijskoga ucinka probiotickog jogurta i zvakace gume koja sadrzava ksilitol kod gerijatrijskih pacijenata: randomizirano kontrolirano klinicko istrazivanje

• Published in: Acta stomatologica croatica 2021-12, Vol.55 (4), p.380
• Main Authors: Gad, Hadier Mahmoud Ahmed, Riad, Mona Ismail, Shaalan, Omar
• Format: Article
• Language: English
• Subjects: Aged patients; Antibacterial agents; Chewing gum; Clinical trials; Comparative analysis; Xylitol; Yogurt
• ISSN: 0001-7019
• DOI: 10.15644/asc55M/5

Objectives: To evaluate the effect of probiotic bacteria in yogurt on Streptococcus mutans (MS) count, plaque adherence and salivary pH compared to xylitol-containing chewing gum in geriatric patients. Material and methods: Total number of 96 high caries risk geriatric patients were randomized into two equal groups (n=48). Group 1 (intervention group) received probiotic yogurt (Activia, Danone) once per day, and group 2 (control group) received xylitol chewing gum (Trident original) three times per day. The primary outcome was salivary Streptococcus mutans count and secondary outcomes were interdental plaque Streptococcus mutans count, salivary pH and bacterial adherence. Results: For Streptococcus mutans count in saliva and plaque, a statistically significant reduction in the level of MS over all the examined follow up periods of the study in probiotic yogurt group as well as xylitol gum group was found. An intergroup comparison for salivary MS count showed statistically significant difference between the two materials in a two week and a three month period of time and there was no statistically significant difference between both materials at one month time period. Salivary pH results showed statistically significant increase in pH in both groups along the follow-up periods. Bacterial adherence results showed statistically significant reduction in both groups. Conclusions: Probiotic yogurt is an effective antibacterial agent against salivary and plaque bacteria in geriatric patients. Svrha istraZivanja: Procijeniti kod gerijatrijskih pacijenata ucinak probiotickih bakterija u jogurtu prema broju bakterija Streptococcus mutans (SM), adherenciji plaka i pH sline u usporedbi sa zvakacom gumom koja sadrzava ksilitol. Materijali i metode: Ukupan broj od 96 gerijatrijskih pacijenata s visokim rizikom od pojave karijesa randomiziran je u dvije jednake skupine (n = 48). Skupina 1 (in-terventna skupina) konzumirala je probioticki jogurt (Activia, Danone) jedanput na dan, a skupina 2 (kontrolna skupina) dobivala je zvakacu gumu sa ksilitolom (Trident original) tri puta na dan. Primarni ishod bio je broj bakterija Streptococcus mutans u slini, a sekundarno se zelio doznati broj tih bakterija u interdentalnom plaku, pH sline i adherencija SM-a. Rezultati: Za broj bakterija Streptococcus mutans u slini i plaku postignuto je statisticki znacajno smanjenje njihove razine tijekom svih razdo-blja pracenja u skupini s probiotickim jogurtom te u skupini sa zvakacom gumom k