Synthesis and Anticancer Activity of 1,3,4-Oxadiazole-oxazolo[4,5-b]pyridine Derivatives

A number of 1,3,4-oxadiazole incorporated oxazolo[4,5- b ]pyridine derivatives has been synthesized, characterized and tested for anticancer activity against four human cancer cell lines including breast cancer (MCF-7), lung cancer (A549), colon cancer (Colo-205), and ovarian cancer (A2780) using et...

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Bibliographic Details
Published in:Russian journal of general chemistry 2020-07, Vol.90 (7), p.1331-1335
Main Authors: Kokkiligadda, Suresh Babu, Musunuri, Sivanadh, Maiti, Bhimcharan, Rao, M. V. Basaveswara, Sridhar, Gattu
Format: Article
Language:English
Subjects:
Benoxaprofen
Cancer
Care and treatment
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Colon cancer
Drug approval
Etoposide
Lung cancer
Pyridine
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Summary:A number of 1,3,4-oxadiazole incorporated oxazolo[4,5- b ]pyridine derivatives has been synthesized, characterized and tested for anticancer activity against four human cancer cell lines including breast cancer (MCF-7), lung cancer (A549), colon cancer (Colo-205), and ovarian cancer (A2780) using etoposide as a standard drug. All products demonstrate good anticancer activity, several compounds can be considered as promising anticancer agents.
ISSN:1070-3632
1608-3350
DOI:10.1134/S107036322007021X