Synthesis of novel [gamma]-butyrolactone-based phenazine compounds via microwave-assisted multicomponent domino reactions

A series of new and significative [gamma]-butyrolactone-based phenazines were synthesized through two-step one-pot five-component reactions of 2-hydroxy-1,4-naphthoquinone, a variety of aromatic aldehydes, benzene-1,2-diamine, tetronic acid, and ammonium acetate in glacial acetic acid. The synthesis...

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Bibliographic Details
Published in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2022-12, Vol.58 (12), p.749
Main Authors: Nguyen, Ha-Thanh, Thi, Phuong Hoang, Le-Nhat-Thuy, Giang, Thi, Quynh Giang Nguyen, Nguyen, Tuan Anh, Thi, Tuyet Anh Dang, Van Nguyen, Tuyen
Format: Article
Language:English
Subjects:
Acetates
Acetic acid
Drospirenone
Lactones
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Summary:A series of new and significative [gamma]-butyrolactone-based phenazines were synthesized through two-step one-pot five-component reactions of 2-hydroxy-1,4-naphthoquinone, a variety of aromatic aldehydes, benzene-1,2-diamine, tetronic acid, and ammonium acetate in glacial acetic acid. The synthesis proceeded via condensation, Michael addition, tautomerization sequence of steps. All the synthesized compounds were fully characterized by spectral data.
ISSN:0009-3122
DOI:10.1007/s10593-023-03152-8