Total fat and alpha-tocopherol in breast milk: is there a relationship after supplementation with vitamin E?/Lipideos totais e alfa-tocoferol no leite maduro: existe relacao apos suplementacao com vitamina E?

• Published in: Demetra: Alimentação, Nutrição e Saúde Nutrição e Saúde, 2022-01, Vol.17, p.1
• Main Authors: de Medeiros, Juliane Oliveira, de Sousa Reboucas, Amanda, Dimenstein, Roberto, da Silva Ribeiro Rodrigues, Karla Danielly
• Format: Article
• Language: Portuguese
• ISSN: 2238-913X; 2238-913X
• DOI: 10.12957/demetra.2022.65415

Introduction: Fat intake during lactation may modify the concentration of vitamin E in human milk, probably because both nutrients are fat soluble and also share similar pathways of distribution, metabolism and molecular action. It is known that the high maternal vitamin E intake through supplementation alters alpha-tocopherol concentration in breast milk, but the relationship with human milk lipids has not yet been studied. Objective: This study aims to evaluate the association between alpha-tocopherol and total fat in breast milk after maternal supplementation with megadoses of vitamin E. Method: This study is part of a clinical trial composed of lactating women from a public outpatient clinic in the city of Natal, RN, Brasil. The group studied were 26 lactating women from a supplemented group whom were given a single dose of 800 IU of RRR-alpha-tocopherol (588 mg) between 30 and 90 days postpartum. Breast milk was collected before and 24h after supplementation. The food intake was assessed by a 24-hour Dietary Recall, the concentration of alpha-tocopherol was determined by high-performance liquid chromatography, and lipid concentration was determined by a creamatocrit analyzer. Results: All participants had inadequate vitamin intake (