Natural Products and Synthetic Derivatives as Promising Candidates Against Neglected Tropical Diseases

Neglected Tropical Diseases (NTD) are a group of endemic diseases that cause up to one million deaths annually. Leishmaniasis and Chagas Disease are classified as NTD whose current treatments are of limited access. There is an urgent need to develop new agents to combat or alleviate the symptoms of...

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Bibliographic Details
Published in:Orbital : The Electronic Journal of Chemistry 2022-10, Vol.14 (4), p.247
Main Authors: Fuzaro, Ana Flavia dos Santos, Ponciano, Carolina S, Barros, Jose C, Grazul, Richard M, Almeida, Mauro Vieira de, Avila, Eloah Pereira
Format: Article
Language:English
Subjects:
Chagas' disease
Leishmaniasis
Medical research
Medicine, Experimental
Online Access:Get full text
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Summary:Neglected Tropical Diseases (NTD) are a group of endemic diseases that cause up to one million deaths annually. Leishmaniasis and Chagas Disease are classified as NTD whose current treatments are of limited access. There is an urgent need to develop new agents to combat or alleviate the symptoms of these pathologies. The present work highlights the activities of several natural products and their derivatives which have been tested against the causative parasites of both diseases. The activities of natural products illustrate their potential to assist in the combat against NTD. Research in this area could provide an opportunity to advance medical research and to provide treatments to low-and middle-income countries. Keywords Chagas disease Leishmaniasis Natural products Neglected Tropical Diseases--NTD Trypanosomiasis
ISSN:1984-6428
1984-6428
DOI:10.17807/orbital.v1414.16374