NISCH and CDH1 Promoter Hypermethylation in Lung Cancer: A Case Control Study

The high mortality of lung cancer is attributable to presence of metastatic disease in nearly two-thirds of patients at diagnosis. Detection of early stage lung cancer amenable to curative resection could boost survival. Cancer specific methylation patterns of tumor suppressor genes, which precede p...

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Bibliographic Details
Published in:Indian journal of clinical biochemistry 2022-05, Vol.30 (S1), p.S37
Main Authors: Krishnamurthy, Kritika, Mishra, T.K, Saxena, Alpana, Daga, M.K, Khurana, Nita, Mirza, Masroor
Format: Article
Language:English
Subjects:
Analysis
Cancer
Development and progression
Health aspects
Lung cancer
Metastasis
Methylation
Mortality
Oncology, Experimental
Smokers
Sulfites
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Summary:The high mortality of lung cancer is attributable to presence of metastatic disease in nearly two-thirds of patients at diagnosis. Detection of early stage lung cancer amenable to curative resection could boost survival. Cancer specific methylation patterns of tumor suppressor genes, which precede precursor lesions, could possibly herald earlier diagnosis.
ISSN:0970-1915